To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...] View this page in https
ENZYME entry: EC 188.8.131.52
View entry in original ENZYME format
View entry in raw text format (no links)
in this entry
|Senecionine monooxygenase (N-oxide-forming).|
|Senecionine + NADPH + O(2) <=> senecionine N-oxide + NADP(+) + H(2)O|
- NADH cannot replace NADPH.
- While pyrrolizidine alkaloids of the senecionine and monocrotaline
types are generally good substrates (e.g. senecionine, retrorsine and
monocrotaline), the enzyme does not use ester alkaloids lacking an
hydroxy group at C-7 (e.g. supinine and phalaenopsine), 1,2-dihydro-
alkaloids (e.g. sarracine) or unesterified necine bases (e.g.
senkirkine) as substrates.
- Senecionine N-oxide is used by insects as a chemical defense: it is
non-toxic, but it is bioactivated to a toxic form by the action of
cytochrome P450 oxidase when absorbed by insectivores.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
, with possibility to download in different formats, align etc.
entries corresponding to 1.14.13.-
entries corresponding to 1.14.-.-
entries corresponding to 1.-.-.-