ENZYME entry: EC 1.14.13.119

Accepted Name
5-epiaristolochene 1,3-dihydroxylase.
Alternative Name(s)
5-epi-aristolochene 1,3-dihydroxylase.
CYP71D20.
EAH.
Reaction catalysed
5-epiaristolochene + 2 NADPH + 2 O(2) <=> capsidiol + 2 NADP(+) + 2 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • Kinetic studies suggest that 1-beta-hydroxyepiaristolochene is mainly formed first followed by hydroxylation at C-3.
  • However the reverse order via 3-alpha-hydroxyepiaristolochene does occur.
Cross-references
PROSITEPDOC00081
BRENDA1.14.13.119
EC2PDB1.14.13.119
ExplorEnz1.14.13.119
PRIAM enzyme-specific profiles1.14.13.119
KEGG Ligand Database for Enzyme Nomenclature1.14.13.119
IUBMB Enzyme Nomenclature1.14.13.119
IntEnz1.14.13.119
MEDLINEFind literature relating to 1.14.13.119
MetaCyc1.14.13.119
UniProtKB/Swiss-Prot
Q94FM7, C71DK_TOBAC

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