ENZYME entry: EC 1.14.13.84

Accepted Name
4-hydroxyacetophenone monooxygenase.
Alternative Name(s)
HAPMO.
Reaction catalysed
(4-hydroxyphenyl)ethan-1-one + NADPH + O(2) <=> 4-hydroxyphenyl acetate + NADP(+) + H(2)O
Cofactor(s)
FAD.
Comment(s)
  • The enzyme from Pseudomonas fluorescens ACB catalyzes the conversion of a wide range of acetophenone derivatives.
  • Highest activity occurs with compounds bearing an electron-donating substituent at the para position of the aromatic ring.
  • In the absence of substrate, the enzyme can act as an NADPH oxidase (EC 1.6.3.1).
Cross-references
BRENDA1.14.13.84
EC2PDB1.14.13.84
ExplorEnz1.14.13.84
PRIAM enzyme-specific profiles1.14.13.84
KEGG Ligand Database for Enzyme Nomenclature1.14.13.84
IUBMB Enzyme Nomenclature1.14.13.84
IntEnz1.14.13.84
MEDLINEFind literature relating to 1.14.13.84
MetaCyc1.14.13.84
UniProtKB/Swiss-Prot
Q93TJ5, HAPMO_PSEFL

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-