ENZYME entry: EC 1.14.13.84
| Accepted Name |
|---|
| 4-hydroxyacetophenone monooxygenase.
|
| Alternative Name(s) |
|---|
| HAPMO. |
| Reaction catalysed |
|---|
| (4-hydroxyphenyl)ethan-1-one + NADPH + O(2) <=> 4-hydroxyphenyl acetate + NADP(+) + H(2)O |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- The enzyme from Pseudomonas fluorescens ACB catalyzes the conversion
of a wide range of acetophenone derivatives.
- Highest activity occurs with compounds bearing an electron-donating
substituent at the para position of the aromatic ring.
- In the absence of substrate, the enzyme can act as an NADPH oxidase
(EC 1.6.3.1).
|
| Cross-references |
|---|
| BRENDA | 1.14.13.84 |
| EC2PDB | 1.14.13.84 |
| ExplorEnz | 1.14.13.84 |
| PRIAM enzyme-specific profiles | 1.14.13.84 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.84 |
| IUBMB Enzyme Nomenclature | 1.14.13.84 |
| IntEnz | 1.14.13.84 |
| MEDLINE | Find literature relating to 1.14.13.84 |
| MetaCyc | 1.14.13.84 |
| UniProtKB/Swiss-Prot |
|
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