ENZYME entry: EC 1.17.1.3
| Accepted Name |
|---|
| Leucoanthocyanidin reductase.
|
| Alternative Name(s) |
|---|
| Leucocyanidin reductase. |
| Reaction catalysed |
|---|
| (2R,3S)-catechin + NADP(+) + H(2)O <=> 2,3-trans-3,4-cis-leucocyanidin + NADPH |
| Comment(s) |
|---|
- Catalyzes the synthesis of catechin, catechin-4-beta-ol
(leucocyanidin) and the related flavan-3-ols afzelechin and
gallocatechin, which are initiating monomers in the synthesis of
plant polymeric proanthocyanidins or condensed tannins.
- While 2,3-trans-3,4-cis-leucocyanidin is the preferred flavan-3,4-
diol substrate, 2,3-trans-3,4-cis-leucodelphinidin and 2,3-trans-3,
4-cis-leucopelargonidin can also act as substrates, but more slowly.
- NADH can replace NADPH but is oxidized more slowly.
|
| Cross-references |
|---|
| BRENDA | 1.17.1.3 |
| EC2PDB | 1.17.1.3 |
| ExplorEnz | 1.17.1.3 |
| PRIAM enzyme-specific profiles | 1.17.1.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.17.1.3 |
| IUBMB Enzyme Nomenclature | 1.17.1.3 |
| IntEnz | 1.17.1.3 |
| MEDLINE | Find literature relating to 1.17.1.3 |
| MetaCyc | 1.17.1.3 |
| UniProtKB/Swiss-Prot |
|
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