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ENZYME entry: EC

Accepted Name
Vitamin-K-epoxide reductase (warfarin-insensitive).
Alternative Name(s)
Vitamin K 2,3-epoxide reductase.
Reaction catalysed
3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol
  • Vitamin K 2,3-epoxide is reduced to 3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithiothreitol, which is oxidized to a disulfide.
  • Not inhibited by warfarin (cf. EC
  • Formerly EC
PRIAM enzyme-specific profiles1.17.4.5
KEGG Ligand Database for Enzyme Nomenclature1.17.4.5
IUBMB Enzyme Nomenclature1.17.4.5
MEDLINEFind literature relating to

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
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