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ENZYME entry: EC 22.214.171.124
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|Malonyl CoA reductase (malonate semialdehyde-forming).
|Malonyl CoA reductase (NADP).|
|NADP-dependent malonyl CoA reductase.|
|Malonate semialdehyde + CoA + NADP(+) <=> malonyl-CoA + NADPH|
- Catalyzes the reduction of malonyl-CoA to malonate semialdehyde,
a key step in the 3-hydroxypropanoate and the
3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2)
fixation pathways found in some green non-sulfur phototrophic
bacteria and some thermoacidophilic archaea, respectively.
- The enzyme from Sulfolobus tokodaii has been purified, and found to
contain one RNA molecule per two subunits.
- The enzyme from Chloroflexus aurantiacus is bifunctional, and also
catalyzes the next reaction in the pathway, EC 126.96.36.1998.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
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