ENZYME entry: EC 1.2.1.80

Accepted Name
Long-chain acyl-[acyl-carrier-protein] reductase.
Alternative Name(s)
Fatty acyl-[acyl-carrier-protein] reductase.
Reaction catalysed
A long-chain aldehyde + an [acyl-carrier protein] + NAD(P)(+) <=> a long-chain acyl-[acyl-carrier protein] + NAD(P)H
Cofactor(s)
Mg(2+).
Comment(s)
  • Catalyzes the reaction in the opposite direction.
  • This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyzes the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde.
  • Together with EC 4.1.99.5, it is involved in alkane biosynthesis.
  • The natural substrates of the enzyme are C16 to C18 activated fatty acids.
Cross-references
BRENDA1.2.1.80
EC2PDB1.2.1.80
ExplorEnz1.2.1.80
PRIAM enzyme-specific profiles1.2.1.80
KEGG Ligand Database for Enzyme Nomenclature1.2.1.80
IUBMB Enzyme Nomenclature1.2.1.80
IntEnz1.2.1.80
MEDLINEFind literature relating to 1.2.1.80
MetaCyc1.2.1.80
UniProtKB/Swiss-Prot
Q54765, AAR_SYNE7;  Q55687, AAR_SYNY3;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
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