ENZYME entry: EC 1.2.1.84

Accepted Name
Alcohol-forming fatty acyl-CoA reductase.
Reaction catalysed
A long-chain acyl-CoA + 2 NADPH <=> CoA + a long-chain alcohol + 2 NADP(+)
Comment(s)
  • The enzyme has been characterized from the plant Simmondsia chinensis (jojoba).
  • The alcohol is formed by a four-electron reduction of fatty acyl-CoA.
  • Although the reaction proceeds through an aldehyde intermediate, a free aldehyde is not released.
  • The recombinant enzyme was shown to accept saturated and mono- unsaturated fatty acyl-CoAs of 16 to 22 carbons.
Cross-references
BRENDA1.2.1.84
EC2PDB1.2.1.84
ExplorEnz1.2.1.84
PRIAM enzyme-specific profiles1.2.1.84
KEGG Ligand Database for Enzyme Nomenclature1.2.1.84
IUBMB Enzyme Nomenclature1.2.1.84
IntEnz1.2.1.84
MEDLINEFind literature relating to 1.2.1.84
MetaCyc1.2.1.84
UniProtKB/Swiss-Prot
Q9XGY7, FAR_SIMCH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
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