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ENZYME entry: EC

Accepted Name
Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific).
Alternative Name(s)
Acyl-ACP dehydrogenase.
Enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific).
Reaction catalysed
An acyl-[acyl-carrier protein] + NADP(+) <=> a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH
  • This enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to an acyl- carrier protein.
  • It is one of the activities of EC
  • The mammalian enzyme is Re-specific with respect to NADP(+) (cf. EC and and EC
PRIAM enzyme-specific profiles1.3.1.39
KEGG Ligand Database for Enzyme Nomenclature1.3.1.39
IUBMB Enzyme Nomenclature1.3.1.39
MEDLINEFind literature relating to
P12276, FAS_CHICK;  P49327, FAS_HUMAN;  P19096, FAS_MOUSE;  
P12785, FAS_RAT;  

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