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ENZYME entry: EC

Accepted Name
(S)-6-hydroxynicotine oxidase.
Alternative Name(s)
6-hydroxy-L-nicotine oxidase.
L-6-hydroxynicotine oxidase.
Reaction catalysed
(S)-6-hydroxynicotine + H(2)O + O(2) <=> 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H(2)O(2)
  • The enzyme, which participates in nicotine degradation, is specific for the (S) isomer of 6-hydroxynicotine.
  • The bacterium Arthrobacter nicotinovorans, in which this enzyme was originally discovered, has a different enzyme that catalyzes a similar reaction with the less common (R)-isomer (cf. EC
PRIAM enzyme-specific profiles1.5.3.5
KEGG Ligand Database for Enzyme Nomenclature1.5.3.5
IUBMB Enzyme Nomenclature1.5.3.5
MEDLINEFind literature relating to

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