| Accepted Name |
|---|
| NADPH--hemoprotein reductase.
|
| Alternative Name(s) |
|---|
| Aldehyde reductase (NADPH-dependent). |
| CPR. |
| Cytochrome c reductase (reduced nicotinamide adenine dinucleotide
phosphate, NADPH, NADPH-dependent). |
| Cytochrome P450 reductase. |
| Dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c
reductase. |
| FAD-cytochrome c reductase. |
| Ferrihemoprotein P-450 reductase. |
| NADP--cytochrome c reductase. |
| NADP--cytochrome reductase. |
| NADPH--cytochrome c oxidoreductase. |
| NADPH--cytochrome c reductase. |
| NADPH--cytochrome P450 oxidoreductase. |
| NADPH--cytochrome P450 reductase. |
| NADPH--ferricytochrome c oxidoreductase. |
| NADPH--ferrihemoprotein reductase. |
| NADPH-dependent cytochrome c reductase. |
| NADPH:ferrihemoprotein oxidoreductase. |
| NADPH:P450 reductase. |
| Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c
reductase. |
| Reductase, cytochrome c (reduced nicotinamide adenine dinucleotide
phosphate). |
| TPNH(2) cytochrome c reductase. |
| TPNH-cytochrome c reductase. |
| Reaction catalysed |
|---|
| NADPH + n oxidized hemoprotein <=> NADP(+) + n reduced hemoprotein |
| Cofactor(s) |
|---|
| FAD; FMN.
|
| Comment(s) |
|---|
- The number n in the equation is 1 if the hemoprotein undergoes a
2-electron reduction, and is 2 if it undergoes a 1-electron
reduction.
- The enzyme catalyzes the reduction of the heme-thiolate-dependent
monooxygenases, such as EC 1.14.14.1, and reduction of EC 1.14.99.3.
- It is part of the microsomal hydroxylating system.
- It also reduces cytochrome b5 and cytochrome c.
|
| Cross-references |
|---|
| BRENDA | 1.6.2.4 |
| EC2PDB | 1.6.2.4 |
| ExplorEnz | 1.6.2.4 |
| PRIAM enzyme-specific profiles | 1.6.2.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.6.2.4 |
| IUBMB Enzyme Nomenclature | 1.6.2.4 |
| IntEnz | 1.6.2.4 |
| MEDLINE | Find literature relating to 1.6.2.4 |
| MetaCyc | 1.6.2.4 |
| UniProtKB/Swiss-Prot |
| Q9SB48, ATR1_ARATH; | Q9Y8G7, C505_FUSOX; | P14779, CPXB_BACME; |
| O08394, CYPD_BACSU; | O08336, CYPE_BACSU; | Q9SUM3, NCPR_ARATH; |
| Q4WM67, NCPR_ASPFU; | A2QS05, NCPR_ASPNC; | Q00141, NCPR_ASPNG; |
| Q2UHA7, NCPR_ASPOR; | Q0CMM0, NCPR_ASPTN; | Q3SYT8, NCPR_BOVIN; |
| P50126, NCPR_CANMA; | P37201, NCPR_CANTR; | Q05001, NCPR_CATRO; |
| P37039, NCPR_CAVPO; | Q27597, NCPR_DROME; | Q5BFT5, NCPR_EMENI; |
| P16435, NCPR_HUMAN; | P37040, NCPR_MOUSE; | Q07994, NCPR_MUSDO; |
| Q9HDG2, NCPR_PHACH; | P04175, NCPR_PIG; | P00389, NCPR_RABIT; |
| P00388, NCPR_RAT; | P19618, NCPR_SALTR; | P36587, NCPR_SCHPO; |
| P37116, NCPR_VIGRR; | P16603, NCPR_YEAST; |
|