Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.

ENZYME entry: EC 1.8.1.14

Accepted Name
CoA-disulfide reductase.
Alternative Name(s)
CoA-disulfide reductase (NAD(P)H).
CoADR.
Coenzyme A disulfide reductase.
NADH:CoA-disulfide oxidoreductase.
Reaction catalysed
2 CoA + NADP(+) <=> CoA-disulfide + NADPH
Cofactor(s)
FAD.
Comment(s)
  • Not identical with EC 1.8.1.6, EC 1.8.1.7 or EC 1.8.1.13.
  • The enzyme from the bacterium Staphylococcus aureus has a strong preference for NADPH, while the bacterium Bacillus megaterium contains both NADH and NADPH-dependent enzymes.
  • Formerly EC 1.6.4.10.
Cross-references
BRENDA1.8.1.14
EC2PDB1.8.1.14
ExplorEnz1.8.1.14
PRIAM enzyme-specific profiles1.8.1.14
KEGG Ligand Database for Enzyme Nomenclature1.8.1.14
IUBMB Enzyme Nomenclature1.8.1.14
IntEnz1.8.1.14
MEDLINEFind literature relating to 1.8.1.14
MetaCyc1.8.1.14
UniProtKB/Swiss-Prot
Q9UYU5, CDR_PYRAB;  Q8U1M0, CDR_PYRFU;  O58308, CDR_PYRHO;  
A7X0I7, CDR_STAA1;  A6U077, CDR_STAA2;  Q2FIA5, CDR_STAA3;  
O52582, CDR_STAA8;  A5IRE8, CDR_STAA9;  Q2YWW1, CDR_STAAB;  
Q5HHB4, CDR_STAAC;  A6QFI1, CDR_STAAE;  Q99VC0, CDR_STAAM;  
Q7A6H1, CDR_STAAN;  Q6GIB7, CDR_STAAR;  Q6GAV6, CDR_STAAS;  
A8Z076, CDR_STAAT;  Q8NXE8, CDR_STAAW;  Q5HQI9, CDR_STAEQ;  
Q8CPT6, CDR_STAES;  Q4L4Y7, CDR_STAHJ;  Q49WB0, CDR_STAS1;  
Q5JGP4, CDR_THEKO;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-