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ENZYME entry: EC

Accepted Name
Enzyme-thiol transhydrogenase (glutathione-disulfide).
Alternative Name(s)
[Xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase.
Enzyme-thiol transhydrogenase (oxidized-glutathione).
Glutathione-dependent thiol:disulfide oxidoreductase.
Thiol:disulfide oxidoreductase.
Reaction catalysed
[Xanthine dehydrogenase] + glutathione disulfide <=> [xanthine oxidase] + 2 glutathione
  • Converts EC into EC in the presence of glutathione disulfide.
  • Also reduces the disulfide bond of ricin.
  • Not inhibited by Cu(2+) or thiol reagents.
PRIAM enzyme-specific profiles1.8.4.7
KEGG Ligand Database for Enzyme Nomenclature1.8.4.7
IUBMB Enzyme Nomenclature1.8.4.7
MEDLINEFind literature relating to

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