ENZYME entry: EC 2.1.1.116

Accepted Name
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine <=> S-adenosyl-L-homocysteine + (S)-reticuline
Comment(s)
  • Involved in isoquinoline alkaloid metabolism in plants.
  • Has also been shown to catalyze the methylation of (RS)- laudanosoline, (S)-3'-hydroxycoclaurine and (RS)-7- O-methylnoraudanosoline.
Cross-references
BRENDA2.1.1.116
EC2PDB2.1.1.116
ExplorEnz2.1.1.116
PRIAM enzyme-specific profiles2.1.1.116
KEGG Ligand Database for Enzyme Nomenclature2.1.1.116
IUBMB Enzyme Nomenclature2.1.1.116
IntEnz2.1.1.116
MEDLINEFind literature relating to 2.1.1.116
MetaCyc2.1.1.116
UniProtKB/Swiss-Prot
Q7XB11, 4OMT1_PAPSO;  Q7XB10, 4OMT2_PAPSO;  Q9LEL5, 4OMT_COPJA;  

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