ENZYME class: 2.1.1

Release of 03-Sep-14


Transferases
Transferring one-carbon groups
Methyltransferases

All UniProtKB/Swiss-Prot entries corresponding to class 2.1.1.-.

The following ENZYME entries belong to class 2.1.1.-:

2.1.1.1      Nicotinamide N-methyltransferase.
2.1.1.2      Guanidinoacetate N-methyltransferase.
2.1.1.3      Thetin--homocysteine S-methyltransferase.
2.1.1.4      Acetylserotonin O-methyltransferase.
2.1.1.5      Betaine--homocysteine S-methyltransferase.
2.1.1.6      Catechol O-methyltransferase.
2.1.1.7      Nicotinate N-methyltransferase.
2.1.1.8      Histamine N-methyltransferase.
2.1.1.9      Thiol S-methyltransferase.
2.1.1.10     Homocysteine S-methyltransferase.
2.1.1.11     Magnesium protoporphyrin IX methyltransferase.
2.1.1.12     Methionine S-methyltransferase.
2.1.1.13     Methionine synthase.
2.1.1.14     5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.
2.1.1.15     Fatty-acid O-methyltransferase.
2.1.1.16     Methylene-fatty-acyl-phospholipid synthase.
2.1.1.17     Phosphatidylethanolamine N-methyltransferase.
2.1.1.18     Polysaccharide O-methyltransferase.
2.1.1.19     Trimethylsulfonium--tetrahydrofolate N-methyltransferase.
2.1.1.20     Glycine N-methyltransferase.
2.1.1.21     Methylamine--glutamate N-methyltransferase.
2.1.1.22     Carnosine N-methyltransferase.
2.1.1.23     Transferred entry: 2.1.1.124, 2.1.1.125 and 2.1.1.126.
2.1.1.24     Transferred entry: 2.1.1.77, 2.1.1.80 and 2.1.1.100.
2.1.1.25     Phenol O-methyltransferase.
2.1.1.26     Iodophenol O-methyltransferase.
2.1.1.27     Tyramine N-methyltransferase.
2.1.1.28     Phenylethanolamine N-methyltransferase.
2.1.1.29     Transferred entry: 2.1.1.202, 2.1.1.203 and 2.1.1.204.
2.1.1.30     Deleted entry.
2.1.1.31     Transferred entry: 2.1.1.221 and 2.1.1.228.
2.1.1.32     Transferred entry: 2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216.
2.1.1.33     tRNA (guanine(46)-N(7))-methyltransferase.
2.1.1.34     tRNA (guanosine(18)-2'-O)-methyltransferase.
2.1.1.35     tRNA (uracil(54)-C(5))-methyltransferase.
2.1.1.36     Transferred entry: 2.1.1.217, 2.1.1.218, 2.1.1.219 and 2.1.1.220.
2.1.1.37     DNA (cytosine-5-)-methyltransferase.
2.1.1.38     O-demethylpuromycin O-methyltransferase.
2.1.1.39     Inositol 3-methyltransferase.
2.1.1.40     Inositol 1-methyltransferase.
2.1.1.41     Sterol 24-C-methyltransferase.
2.1.1.42     Flavone 3'-O-methyltransferase.
2.1.1.43     Histone-lysine N-methyltransferase.
2.1.1.44     L-histidine N(alpha)-methyltransferase.
2.1.1.45     Thymidylate synthase.
2.1.1.46     Isoflavone 4'-O-methyltransferase.
2.1.1.47     Indolepyruvate C-methyltransferase.
2.1.1.48     Transferred entry: 2.1.1.181, 2.1.1.182, 2.1.1.183 and 2.1.1.184.
2.1.1.49     Amine N-methyltransferase.
2.1.1.50     Loganate O-methyltransferase.
2.1.1.51     Transferred entry: 2.1.1.187 and 2.1.1.188.
2.1.1.52     Transferred entry: 2.1.1.171, 2.1.1.172, 2.1.1.173 and 2.1.1.174.
2.1.1.53     Putrescine N-methyltransferase.
2.1.1.54     Deoxycytidylate C-methyltransferase.
2.1.1.55     tRNA (adenine-N(6)-)-methyltransferase.
2.1.1.56     mRNA (guanine-N(7)-)-methyltransferase.
2.1.1.57     Methyltransferase cap1.
2.1.1.58     Transferred entry: 2.1.1.57.
2.1.1.59     [Cytochrome c]-lysine N-methyltransferase.
2.1.1.60     Calmodulin-lysine N-methyltransferase.
2.1.1.61     tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase.
2.1.1.62     mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase.
2.1.1.63     Methylated-DNA--[protein]-cysteine S-methyltransferase.
2.1.1.64     3-demethylubiquinol 3-O-methyltransferase.
2.1.1.65     Licodione 2'-O-methyltransferase.
2.1.1.66     Transferred entry: 2.1.1.230.
2.1.1.67     Thiopurine S-methyltransferase.
2.1.1.68     Caffeate O-methyltransferase.
2.1.1.69     5-hydroxyfuranocoumarin 5-O-methyltransferase.
2.1.1.70     8-hydroxyfuranocoumarin 8-O-methyltransferase.
2.1.1.71     Phosphatidyl-N-methylethanolamine N-methyltransferase.
2.1.1.72     Site-specific DNA-methyltransferase (adenine-specific).
2.1.1.73     Transferred entry: 2.1.1.37.
2.1.1.74     Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase
             (FADH(2)-oxidizing).
2.1.1.75     Apigenin 4'-O-methyltransferase.
2.1.1.76     Quercetin 3-O-methyltransferase.
2.1.1.77     Protein-L-isoaspartate(D-aspartate) O-methyltransferase.
2.1.1.78     Isoorientin 3'-O-methyltransferase.
2.1.1.79     Cyclopropane-fatty-acyl-phospholipid synthase.
2.1.1.80     Protein-glutamate O-methyltransferase.
2.1.1.81     Transferred entry: 2.1.1.49.
2.1.1.82     3-methylquercetin 7-O-methyltransferase.
2.1.1.83     3,7-dimethylquercetin 4'-O-methyltransferase.
2.1.1.84     Methylquercetagetin 6-O-methyltransferase.
2.1.1.85     Protein-histidine N-methyltransferase.
2.1.1.86     Tetrahydromethanopterin S-methyltransferase.
2.1.1.87     Pyridine N-methyltransferase.
2.1.1.88     8-hydroxyquercetin 8-O-methyltransferase.
2.1.1.89     Tetrahydrocolumbamine 2-O-methyltransferase.
2.1.1.90     Methanol--corrinoid protein Co-methyltransferase.
2.1.1.91     Isobutyraldoxime O-methyltransferase.
2.1.1.92     Transferred entry: 2.1.1.69.
2.1.1.93     Transferred entry: 2.1.1.70.
2.1.1.94     Tabersonine 16-O-methyltransferase.
2.1.1.95     Tocopherol O-methyltransferase.
2.1.1.96     Thioether S-methyltransferase.
2.1.1.97     3-hydroxyanthranilate 4-C-methyltransferase.
2.1.1.98     Diphthine synthase.
2.1.1.99     3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase.
2.1.1.100    Protein-S-isoprenylcysteine O-methyltransferase.
2.1.1.101    Macrocin O-methyltransferase.
2.1.1.102    Demethylmacrocin O-methyltransferase.
2.1.1.103    Phosphoethanolamine N-methyltransferase.
2.1.1.104    Caffeoyl-CoA O-methyltransferase.
2.1.1.105    N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase.
2.1.1.106    Tryptophan 2-C-methyltransferase.
2.1.1.107    Uroporphyrinogen-III C-methyltransferase.
2.1.1.108    6-hydroxymellein O-methyltransferase.
2.1.1.109    Demethylsterigmatocystin 6-O-methyltransferase.
2.1.1.110    Sterigmatocystin 8-O-methyltransferase.
2.1.1.111    Anthranilate N-methyltransferase.
2.1.1.112    Glucuronoxylan 4-O-methyltransferase.
2.1.1.113    Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
2.1.1.114    Polyprenyldihydroxybenzoate methyltransferase.
2.1.1.115    (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase.
2.1.1.116    3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase.
2.1.1.117    (S)-scoulerine 9-O-methyltransferase.
2.1.1.118    Columbamine O-methyltransferase.
2.1.1.119    10-hydroxydihydrosanguinarine 10-O-methyltransferase.
2.1.1.120    12-hydroxydihydrochelirubine 12-O-methyltransferase.
2.1.1.121    6-O-methylnorlaudanosoline 5'-O-methyltransferase.
2.1.1.122    (S)-tetrahydroprotoberberine N-methyltransferase.
2.1.1.123    [Cytochrome c]-methionine S-methyltransferase.
2.1.1.124    [Cytochrome c]-arginine N-methyltransferase.
2.1.1.125    Histone-arginine N-methyltransferase.
2.1.1.126    [Myelin basic protein]-arginine N-methyltransferase.
2.1.1.127    [Ribulose-bisphosphate carboxylase]-lysine N-methyltransferase.
2.1.1.128    (RS)-norcoclaurine 6-O-methyltransferase.
2.1.1.129    Inositol 4-methyltransferase.
2.1.1.130    Precorrin-2 C(20)-methyltransferase.
2.1.1.131    Precorrin-3B C(17)-methyltransferase.
2.1.1.132    Precorrin-6B C(5,15)-methyltransferase (decarboxylating).
2.1.1.133    Precorrin-4 C(11)-methyltransferase.
2.1.1.134    Transferred entry: 2.1.1.129.
2.1.1.135    Transferred entry: 1.16.1.8.
2.1.1.136    Chlorophenol O-methyltransferase.
2.1.1.137    Arsenite methyltransferase.
2.1.1.138    Deleted entry.
2.1.1.139    3'-demethylstaurosporine O-methyltransferase.
2.1.1.140    (S)-coclaurine-N-methyltransferase.
2.1.1.141    Jasmonate O-methyltransferase.
2.1.1.142    Cycloartenol 24-C-methyltransferase.
2.1.1.143    24-methylenesterol C-methyltransferase.
2.1.1.144    Trans-aconitate 2-methyltransferase.
2.1.1.145    Trans-aconitate 3-methyltransferase.
2.1.1.146    (Iso)eugenol O-methyltransferase.
2.1.1.147    Corydaline synthase.
2.1.1.148    Thymidylate synthase (FAD).
2.1.1.149    Transferred entry: 2.1.1.267.
2.1.1.150    Isoflavone 7-O-methyltransferase.
2.1.1.151    Cobalt-factor II C(20)-methyltransferase.
2.1.1.152    Precorrin-6A synthase (deacetylating).
2.1.1.153    Vitexin 2''-O-rhamnoside 7-O-methyltransferase.
2.1.1.154    Isoliquiritigenin 2'-O-methyltransferase.
2.1.1.155    Kaempferol 4'-O-methyltransferase.
2.1.1.156    Glycine/sarcosine N-methyltransferase.
2.1.1.157    Sarcosine/dimethylglycine N-methyltransferase.
2.1.1.158    7-methylxanthosine synthase.
2.1.1.159    Theobromine synthase.
2.1.1.160    Caffeine synthase.
2.1.1.161    Dimethylglycine N-methyltransferase.
2.1.1.162    Glycine/sarcosine/dimethylglycine N-methyltransferase.
2.1.1.163    Demethylmenaquinone methyltransferase.
2.1.1.164    Demethylrebeccamycin-D-glucose O-methyltransferase.
2.1.1.165    Methyl halide transferase.
2.1.1.166    23S rRNA (uridine(2552)-2'-O)-methyltransferase.
2.1.1.167    27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase.
2.1.1.168    21S rRNA (uridine(2791)-2'-O)-methyltransferase.
2.1.1.169    Tricetin 3',4',5'-O-trimethyltransferase.
2.1.1.170    16S rRNA (guanine(527)-N(7))-methyltransferase.
2.1.1.171    16S rRNA (guanine(966)-N(2))-methyltransferase.
2.1.1.172    16S rRNA (guanine(1207)-N(2))-methyltransferase.
2.1.1.173    23S rRNA (guanine(2445)-N(2))-methyltransferase.
2.1.1.174    23S rRNA (guanine(1835)-N(2))-methyltransferase.
2.1.1.175    Tricin synthase.
2.1.1.176    16S rRNA (cytosine(967)-C(5))-methyltransferase.
2.1.1.177    23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
2.1.1.178    16S rRNA (cytosine(1407)-C(5))-methyltransferase.
2.1.1.179    16S rRNA (guanine(1405)-N(7))-methyltransferase.
2.1.1.180    16S rRNA (adenine(1408)-N(1))-methyltransferase.
2.1.1.181    23S rRNA (adenine(1618)-N(6))-methyltransferase.
2.1.1.182    16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase.
2.1.1.183    18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase.
2.1.1.184    23S rRNA (adenine(2085)-N(6))-dimethyltransferase.
2.1.1.185    23S rRNA (guanosine(2251)-2'-O)-methyltransferase.
2.1.1.186    23S rRNA (cytidine(2498)-2'-O)-methyltransferase.
2.1.1.187    23S rRNA (guanine(745)-N(1))-methyltransferase.
2.1.1.188    23S rRNA (guanine(748)-N(1))-methyltransferase.
2.1.1.189    23S rRNA (uracil(747)-C(5))-methyltransferase.
2.1.1.190    23S rRNA (uracil(1939)-C(5))-methyltransferase.
2.1.1.191    23S rRNA (cytosine(1962)-C(5))-methyltransferase.
2.1.1.192    23S rRNA (adenine(2503)-C(2))-methyltransferase.
2.1.1.193    16S rRNA (uracil(1498)-N(3))-methyltransferase.
2.1.1.194    Deleted entry.
2.1.1.195    Cobalt-precorrin-5B (C(1))-methyltransferase.
2.1.1.196    Cobalt-precorrin-6B (C(15))-methyltransferase (decarboxylating).
2.1.1.197    Malonyl-[acyl-carrier protein] O-methyltransferase.
2.1.1.198    16S rRNA (cytidine(1402)-2'-O)-methyltransferase.
2.1.1.199    16S rRNA (cytosine(1402)-N(4))-methyltransferase.
2.1.1.200    tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
2.1.1.201    2-methoxy-6-polyprenyl-1,4-benzoquinol methylase.
2.1.1.202    Multisite-specific tRNA:(cytosine-C(5))-methyltransferase.
2.1.1.203    tRNA (cytosine(34)-C(5))-methyltransferase.
2.1.1.204    tRNA (cytosine(38)-C(5))-methyltransferase.
2.1.1.205    tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase.
2.1.1.206    tRNA (cytidine(56)-2'-O)-methyltransferase.
2.1.1.207    tRNA (cytidine(34)-2'-O)-methyltransferase.
2.1.1.208    23S rRNA (uridine(2479)-2'-O)-methyltransferase.
2.1.1.209    23S rRNA (guanine(2535)-N(1))-methyltransferase.
2.1.1.210    Demethylspheroidene O-methyltransferase.
2.1.1.211    tRNA(Ser) (uridine(44)-2'-O)-methyltransferase.
2.1.1.212    2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase.
2.1.1.213    tRNA (guanine(10)-N(2))-dimethyltransferase.
2.1.1.214    tRNA (guanine(10)-N(2))-methyltransferase.
2.1.1.215    tRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase.
2.1.1.216    tRNA (guanine(26)-N(2))-dimethyltransferase.
2.1.1.217    tRNA (adenine(22)-N(1))-methyltransferase.
2.1.1.218    tRNA (adenine(9)-N(1))-methyltransferase.
2.1.1.219    tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase.
2.1.1.220    tRNA (adenine(58)-N(1))-methyltransferase.
2.1.1.221    tRNA (guanine(9)-N(1))-methyltransferase.
2.1.1.222    2-polyprenyl-6-hydroxyphenol methylase.
2.1.1.223    tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase.
2.1.1.224    23S rRNA (adenine(2503)-C(8))-methyltransferase.
2.1.1.225    tRNA:m(4)X modification enzyme.
2.1.1.226    23S rRNA (cytidine(1920)-2'-O)-methyltransferase.
2.1.1.227    16S rRNA (cytidine(1409)-2'-O)-methyltransferase.
2.1.1.228    tRNA (guanine(37)-N(1))-methyltransferase.
2.1.1.229    tRNA (carboxymethyluridine(34)-5-O)-methyltransferase.
2.1.1.230    23S rRNA (adenosine(1067)-2'-O)-methyltransferase.
2.1.1.231    Flavonoid 4'-O-methyltransferase.
2.1.1.232    Naringenin 7-O-methyltransferase.
2.1.1.233    [Phosphatase 2A protein]-leucine-carboxy methyltransferase.
2.1.1.234    dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose
             N,N-dimethyltransferase.
2.1.1.235    dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase.
2.1.1.236    dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase.
2.1.1.237    Mycinamicin III 3''-O-methyltransferase.
2.1.1.238    Mycinamicin VI 2''-O-methyltransferase.
2.1.1.239    L-olivosyl-oleandolide 3-O-methyltransferase.
2.1.1.240    Trans-resveratrol di-O-methyltransferase.
2.1.1.241    2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase.
2.1.1.242    16S rRNA (guanine(1516)-N(2))-methyltransferase.
2.1.1.243    2-ketoarginine methyltransferase.
2.1.1.244    Protein N-terminal methyltransferase.
2.1.1.245    5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein
             Co-methyltransferase.
2.1.1.246    [Methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M
             methyltransferase.
2.1.1.247    [Methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M
             methyltransferase.
2.1.1.248    [Methylamine--corrinoid protein] Co-methyltransferase.
2.1.1.249    [Dimethylamine--corrinoid protein] Co-methyltransferase.
2.1.1.250    [Trimethylamine--corrinoid protein] Co-methyltransferase.
2.1.1.251    Methylated-thiol--coenzyme M methyltransferase.
2.1.1.252    Tetramethylammonium--corrinoid protein Co-methyltransferase.
2.1.1.253    [Methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme
             M methyltransferase.
2.1.1.254    Erythromycin 3''-O-methyltransferase.
2.1.1.255    Geranyl diphosphate 2-C-methyltransferase.
2.1.1.256    tRNA (guanine(6)-N(2))-methyltransferase.
2.1.1.257    tRNA (pseudouridine(54)-N(1))-methyltransferase.
2.1.1.258    5-methyltetrahydrofolate:corrinoid/iron-sulfur protein
             Co-methyltransferase.
2.1.1.259    [Fructose-bisphosphate aldolase]-lysine N-methyltransferase.
2.1.1.260    rRNA small subunit pseudouridine methyltransferase Nep1.
2.1.1.261    4-dimethylallyltryptophan N-methyltransferase.
2.1.1.262    Squalene methyltransferase.
2.1.1.263    Botryococcene C-methyltransferase.
2.1.1.264    23S rRNA (guanine(2069)-N(7))-methyltransferase.
2.1.1.265    Tellurite methyltransferase.
2.1.1.266    23S rRNA (adenine(2030)-N(6))-methyltransferase.
2.1.1.267    Flavonoid 3',5'-methyltransferase.
2.1.1.268    tRNA(Thr) (cytosine(32)-N(3))-methyltransferase.
2.1.1.269    Dimethylsulfoniopropionate demethylase.
2.1.1.270    (+)-6a-hydroxymaackiain 3-O-methyltransferase.
2.1.1.271    Cobalt-precorrin-4 methyltransferase.
2.1.1.272    Cobalt-factor III methyltransferase.
2.1.1.273    Benzoate O-methyltransferase.
2.1.1.274    Salicylate carboxymethyltransferase.
2.1.1.275    Gibberellin A(9) O-methyltransferase.
2.1.1.276    Gibberellin A(4) carboxyl methyltransferase.
2.1.1.277    Anthranilate O-methyltransferase.
2.1.1.278    Indole-3-acetate O-methyltransferase.
2.1.1.279    Trans-anol O-methyltransferase.
2.1.1.280    Selenocysteine Se-methyltransferase.
2.1.1.281    Phenylpyruvate C(3)-methyltransferase.
2.1.1.282    tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-
             methyltransferase.
2.1.1.283    Emodin O-methyltransferase.
2.1.1.284    8-demethylnovobiocic acid C(8)-methyltransferase.
2.1.1.285    Demethyldecarbamoylnovobiocin O-methyltransferase.
2.1.1.286    25S rRNA (adenine(2142)-N(1))-methyltransferase.
2.1.1.287    25S rRNA (adenine(645)-N(1))-methyltransferase.
2.1.1.288    Aklanonic acid methyltransferase.
2.1.1.289    Cobalt-precorrin-7 (C(5))-methyltransferase.
2.1.1.290    tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase.
2.1.1.291    (R,S)-reticuline 7-O-methyltransferase.
2.1.1.292    Carminomycin 4-O-methyltransferase.
2.1.1.293    6-hydroxytryprostatin B O-methyltransferase.
2.1.1.294    3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol
             3-phospho-methyltransferase.
2.1.1.295    2-methyl-6-phytyl-1,4-hydroquinone methyltransferase.
2.1.1.296    Methyltransferase cap2.
2.1.1.297    Peptide chain release factor N(5)-glutamine methyltransferase.
2.1.1.298    Ribosomal protein L3 N(5)-glutamine methyltransferase.
2.1.1.299    Protein N-terminal monomethyltransferase.
2.1.1.300    Pavine N-methyltransferase.
2.1.1.n1     Resorcinol O-methyltransferase.
2.1.1.n2     Transferred entry: 2.1.1.211.
2.1.1.n3     Transferred entry: 2.1.1.280.
2.1.1.n4     Thiocyanate methyltransferase.
2.1.1.n5     Transferred entry: 2.1.1.244.
2.1.1.n6     Transferred entry: 2.1.1.255.
2.1.1.n7     5-pentadecatrienyl resorcinol O-methyltransferase.
2.1.1.n8     Small RNA 2'-O-methyltransferase.
2.1.1.n9     Transferred entry: 2.1.1.274.
2.1.1.n10    Transferred entry: 2.1.1.278.
2.1.1.n11    Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase.
2.1.1.n12    2-phytyl-1,4-naphtoquinone methyltransferase.
2.1.1.n13    Cypemycin N-terminal methyltransferase.
2.1.1.n14    Transferred entry: 2.1.1.300.
2.1.1.n15    Transferred entry: 2.1.1.298.
2.1.1.n16    Transferred entry: 2.1.1.297.