ENZYME entry: EC 2.1.1.129

Accepted Name
Inositol 4-methyltransferase.
Alternative Name(s)
Myo-inositol 4-O-methyltransferase.
Myo-inositol 6-O-methyltransferase.
S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + myo-inositol <=> S-adenosyl-L-homocysteine + 1D-4-O-methyl-myo-inositol
Comment(s)
  • The enzyme from Vigna umbellata is highly specific for S-adenosyl-L- methionine.
  • The enzyme also methylates 1L-1,2,4/3,5-cyclohexanepentol, 2,4,6/3,5- pentahydroxycyclohexanone, D,L-2,3,4,6/5-pentacyclohexanone and 2,2'-anhydro-2-C-hydroxymethyl-myo-inositol, but at lower rates than that of myo-inositol.
  • Formerly EC 2.1.1.134.
Cross-references
BRENDA2.1.1.129
EC2PDB2.1.1.129
ExplorEnz2.1.1.129
PRIAM enzyme-specific profiles2.1.1.129
KEGG Ligand Database for Enzyme Nomenclature2.1.1.129
IUBMB Enzyme Nomenclature2.1.1.129
IntEnz2.1.1.129
MEDLINEFind literature relating to 2.1.1.129
MetaCyc2.1.1.129
UniProtKB/Swiss-Prot
P45986, IMT1_MESCR

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