ENZYME entry: EC 2.1.1.144

Accepted Name
Trans-aconitate 2-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + trans-aconitate <=> S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate
Comment(s)
  • Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly.
  • While the enzyme from Escherichia coli forms (E)-3-(methoxycarbonyl)- pent-2-enedioate as the product, that from Saccharomyces cerevisiae forms (E)-2-(methoxycarbonylmethyl)butenedioate and is therefore classified as a separate enzyme (cf. EC 2.1.1.145).
Cross-references
BRENDA2.1.1.144
EC2PDB2.1.1.144
ExplorEnz2.1.1.144
PRIAM enzyme-specific profiles2.1.1.144
KEGG Ligand Database for Enzyme Nomenclature2.1.1.144
IUBMB Enzyme Nomenclature2.1.1.144
IntEnz2.1.1.144
MEDLINEFind literature relating to 2.1.1.144
MetaCyc2.1.1.144
UniProtKB/Swiss-Prot
A1TP97, TAM_ACIAC;  B9MBN9, TAM_ACIET;  A1W9K6, TAM_ACISJ;  
Q8UH15, TAM_AGRFC;  B9JBE6, TAM_AGRRK;  A1K8U5, TAM_AZOSB;  
A9M6C1, TAM_BRUC2;  Q8YI91, TAM_BRUME;  A5VRJ7, TAM_BRUO2;  
B0CHP1, TAM_BRUSI;  Q8FZM5, TAM_BRUSU;  Q9RX93, TAM_DEIRA;  
A9BVK1, TAM_DELAS;  A7ZLX5, TAM_ECO24;  B7URP6, TAM_ECO27;  
B7MMY3, TAM_ECO45;  B7L7L9, TAM_ECO55;  Q8XAZ2, TAM_ECO57;  
B5Z1X6, TAM_ECO5E;  B7NIJ1, TAM_ECO7I;  B7LZC1, TAM_ECO8A;  
C4ZWT6, TAM_ECOBW;  B1XEA7, TAM_ECODH;  A8A072, TAM_ECOHS;  
A1AB99, TAM_ECOK1;  Q0THR9, TAM_ECOL5;  Q8FHF2, TAM_ECOL6;  
B1IRU1, TAM_ECOLC;  P76145, TAM_ECOLI;  B7N4U4, TAM_ECOLU;  
B6IAS2, TAM_ECOSE;  B1LF96, TAM_ECOSM;  Q1RBP8, TAM_ECOUT;  
A4WAG4, TAM_ENT38;  B7LRD2, TAM_ESCF3;  B5XQT8, TAM_KLEP3;  
B8ISV4, TAM_METNO;  B1LXF6, TAM_METRJ;  B0UPF4, TAM_METS4;  
A0QM44, TAM_MYCA1;  P66886, TAM_MYCBO;  A1KFB7, TAM_MYCBP;  
C1AJX2, TAM_MYCBT;  A4T0W0, TAM_MYCGI;  B2HNX5, TAM_MYCMM;  
A3PTG0, TAM_MYCSJ;  A1U9V4, TAM_MYCSK;  Q1BF27, TAM_MYCSS;  
A5TZ21, TAM_MYCTA;  P9WGA2, TAM_MYCTO;  P9WGA3, TAM_MYCTU;  
A0PN72, TAM_MYCUA;  A1T273, TAM_MYCVP;  Q1QJC0, TAM_NITHX;  
Q3SPQ7, TAM_NITWN;  A6WZN1, TAM_OCHA4;  B6JIA0, TAM_OLICO;  
A6V4P3, TAM_PSEA7;  Q02N15, TAM_PSEAB;  Q9I0S1, TAM_PSEAE;  
B3PTJ5, TAM_RHIE6;  Q2KAZ5, TAM_RHIEC;  Q98K73, TAM_RHILO;  
B5ZUL2, TAM_RHILW;  Q92RC5, TAM_RHIME;  C3M8G8, TAM_RHISN;  
Q0SED2, TAM_RHOJR;  Q2IYT0, TAM_RHOP2;  Q07PZ6, TAM_RHOP5;  
Q6N3T8, TAM_RHOPA;  Q216J6, TAM_RHOPB;  Q133R5, TAM_RHOPS;  
B3QFV9, TAM_RHOPT;  Q32G05, TAM_SHIDS;  Q0T4L2, TAM_SHIF8;  
Q83RE0, TAM_SHIFL;  A6U707, TAM_SINMW;  Q82HD9, TAM_STRAW;  
Q9K3T2, TAM_STRCO;  C5CSI6, TAM_VARPS;  A1JU33, TAM_YERE8;  
A7FGU8, TAM_YERP3;  Q1C6F5, TAM_YERPA;  B2K7X9, TAM_YERPB;  
Q8ZDP7, TAM_YERPE;  A9R6H5, TAM_YERPG;  Q1CHU7, TAM_YERPN;  
A4TLZ2, TAM_YERPP;  Q669E2, TAM_YERPS;  B1JHA2, TAM_YERPY;  

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