ENZYME entry: EC 2.1.1.166

Accepted Name
23S rRNA (uridine(2552)-2'-O)-methyltransferase.
Alternative Name(s)
FTSJ.
Um(2552) 23S ribosomal RNA methyltransferase.
Um2552 methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + uridine(2552) in 23S rRNA <=> S-adenosyl-L-homocysteine + 2'-O-methyluridine(2552) in 23S rRNA
Comment(s)
The enzyme catalyzes the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA.
Cross-references
BRENDA2.1.1.166
EC2PDB2.1.1.166
ExplorEnz2.1.1.166
PRIAM enzyme-specific profiles2.1.1.166
KEGG Ligand Database for Enzyme Nomenclature2.1.1.166
IUBMB Enzyme Nomenclature2.1.1.166
IntEnz2.1.1.166
MEDLINEFind literature relating to 2.1.1.166
MetaCyc2.1.1.166
UniProtKB/Swiss-Prot
A1TQF0, RLME_ACIAC;  Q6F8N1, RLME_ACIAD;  B7GY18, RLME_ACIB3;  
B7I636, RLME_ACIB5;  B2HXD3, RLME_ACIBC;  B0VSM4, RLME_ACIBS;  
A3M851, RLME_ACIBT;  B0VEE9, RLME_ACIBY;  A5G029, RLME_ACICJ;  
B7J8G6, RLME_ACIF2;  B5ENR5, RLME_ACIF5;  A1W8H0, RLME_ACISJ;  
A3MZW0, RLME_ACTP2;  B3H123, RLME_ACTP7;  B0BUF3, RLME_ACTPJ;  
A6VPC2, RLME_ACTSZ;  A0KNF1, RLME_AERHH;  A4SJQ7, RLME_AERS4;  
Q8UHR0, RLME_AGRFC;  B9J9U0, RLME_AGRRK;  B9JSD2, RLME_AGRVS;  
Q0VSS9, RLME_ALCBS;  B6END5, RLME_ALISL;  Q0A769, RLME_ALKEH;  
Q2IPT3, RLME_ANADE;  A7H9A5, RLME_ANADF;  B9KIP4, RLME_ANAMF;  
Q5PAN0, RLME_ANAMM;  Q2GKK2, RLME_ANAPZ;  O28228, RLME_ARCFU;  
Q5P1G0, RLME_AROAE;  A8II77, RLME_AZOC5;  A1K598, RLME_AZOSB;  
C1DFL6, RLME_AZOVD;  A1URN3, RLME_BARBK;  Q6G4Z3, RLME_BARHE;  
Q6G0S9, RLME_BARQU;  A9IMA1, RLME_BART1;  Q1LSK2, RLME_BAUCH;  
Q6MN40, RLME_BDEBA;  Q7VQM8, RLME_BLOFL;  Q493U3, RLME_BLOPB;  
Q2KVR5, RLME_BORA1;  Q0SNJ8, RLME_BORAP;  Q661V2, RLME_BORBP;  
Q7WMD3, RLME_BORBR;  O51293, RLME_BORBU;  B7J1P0, RLME_BORBZ;  
B5RLD9, RLME_BORDL;  Q7W8R6, RLME_BORPA;  A9HYV0, RLME_BORPD;  
Q7VZ56, RLME_BORPE;  B5RRD2, RLME_BORRA;  Q89N72, RLME_BRADU;  
C0QX75, RLME_BRAHW;  A5EHP2, RLME_BRASB;  A4YSS3, RLME_BRASO;  
B2SAY0, RLME_BRUA1;  Q2YKU4, RLME_BRUA2;  Q578H4, RLME_BRUAB;  
A9MBW8, RLME_BRUC2;  C0RLJ5, RLME_BRUMB;  Q8YCD5, RLME_BRUME;  
A5VUZ8, RLME_BRUO2;  A9WYY2, RLME_BRUSI;  Q8FVY1, RLME_BRUSU;  
P57463, RLME_BUCAI;  Q8K9G7, RLME_BUCAP;  Q89AF1, RLME_BUCBP;  
Q057J5, RLME_BUCCC;  B1YMW2, RLME_BURA4;  Q1BXD0, RLME_BURCA;  
B1JZE9, RLME_BURCC;  A0K6C1, RLME_BURCH;  B4E5F3, RLME_BURCJ;  
Q0BGJ2, RLME_BURCM;  Q39HN2, RLME_BURL3;  A9ACL8, RLME_BURM1;  
A3MIQ3, RLME_BURM7;  A2S3Q7, RLME_BURM9;  Q62L80, RLME_BURMA;  
A1V319, RLME_BURMS;  A3NTW3, RLME_BURP0;  Q3JTT5, RLME_BURP1;  
A3N853, RLME_BURP6;  Q63V86, RLME_BURPS;  Q2SUW0, RLME_BURTA;  
A4JDA6, RLME_BURVG;  Q13W47, RLME_BURXL;  Q9A7V4, RLME_CAUCR;  
B0T8J6, RLME_CAUSK;  B3PLQ4, RLME_CELJU;  A0RV28, RLME_CENSY;  
Q11L51, RLME_CHESB;  Q1QSY2, RLME_CHRSD;  Q7NRI3, RLME_CHRVO;  
A8AQ68, RLME_CITK8;  Q47YJ3, RLME_COLP3;  B6J802, RLME_COXB1;  
B6IZD5, RLME_COXB2;  A9KGE6, RLME_COXBN;  A9N8M5, RLME_COXBR;  
Q83BY4, RLME_COXBU;  A7MIM8, RLME_CROS8;  Q1LLA8, RLME_CUPMC;  
Q0K8Y4, RLME_CUPNH;  Q46Z98, RLME_CUPPJ;  B3R1S2, RLME_CUPTR;  
Q47HI2, RLME_DECAR;  A9BML0, RLME_DELAS;  B8FL12, RLME_DESAA;  
C6C068, RLME_DESAD;  Q30YX3, RLME_DESAG;  C0QGP2, RLME_DESAH;  
A8ZT18, RLME_DESOH;  Q6AJ42, RLME_DESPS;  Q729T9, RLME_DESVH;  
B8DNJ4, RLME_DESVM;  A1VC40, RLME_DESVV;  A5EXB6, RLME_DICNV;  
A7ZS75, RLME_ECO24;  B7UJ72, RLME_ECO27;  B7MBU8, RLME_ECO45;  
B7LHP2, RLME_ECO55;  P0C0R8, RLME_ECO57;  B5YS68, RLME_ECO5E;  
B7NKP6, RLME_ECO7I;  B7N363, RLME_ECO81;  B7M085, RLME_ECO8A;  
C4ZSR8, RLME_ECOBW;  B1XGY9, RLME_ECODH;  A8A4Z3, RLME_ECOHS;  
A1AG82, RLME_ECOK1;  Q0TCT1, RLME_ECOL5;  P0C0R9, RLME_ECOL6;  
B1IQU4, RLME_ECOLC;  P0C0R7, RLME_ECOLI;  B7NDG3, RLME_ECOLU;  
B6I1Q2, RLME_ECOSE;  B1LFS9, RLME_ECOSM;  Q1R6F9, RLME_ECOUT;  
C5BFB0, RLME_EDWI9;  Q3YRW8, RLME_EHRCJ;  Q2GGT6, RLME_EHRCR;  
Q5FH15, RLME_EHRRG;  Q5FEH6, RLME_EHRRW;  A4WEZ0, RLME_ENT38;  
B2VGT0, RLME_ERWT9;  Q2N843, RLME_ERYLH;  B7LR46, RLME_ESCF3;  
B0TZQ8, RLME_FRAP2;  Q14HT5, RLME_FRAT1;  A7NAC9, RLME_FRATF;  
Q2A4Z7, RLME_FRATH;  B2SF85, RLME_FRATM;  A0Q526, RLME_FRATN;  
Q0BNB8, RLME_FRATO;  Q5NGD3, RLME_FRATT;  A4IYP4, RLME_FRATW;  
Q5FNQ1, RLME_GLUOX;  Q0BT08, RLME_GRABC;  Q7VLF2, RLME_HAEDU;  
Q4QKJ2, RLME_HAEI8;  P45162, RLME_HAEIN;  B8F4C0, RLME_HAEPS;  
Q0I2R1, RLME_HAES1;  Q2SMM1, RLME_HAHCH;  A1WXX3, RLME_HALHL;  
B9LSX2, RLME_HALLT;  Q5UYP9, RLME_HALMA;  B0R7G3, RLME_HALS3;  
Q9HN40, RLME_HALSA;  Q18E61, RLME_HALWD;  C4K7K8, RLME_HAMD5;  
A4G4B0, RLME_HERAR;  Q0C187, RLME_HYPNA;  Q5QXK8, RLME_IDILO;  
A6T081, RLME_JANMA;  Q28QW4, RLME_JANSC;  B5XSW2, RLME_KLEP3;  
A6TEJ8, RLME_KLEP7;  Q1MRQ0, RLME_LAWIP;  Q5X1A0, RLME_LEGPA;  
A5IHX0, RLME_LEGPC;  Q5ZRT1, RLME_LEGPH;  Q5WT13, RLME_LEGPL;  
B1XXG3, RLME_LEPCP;  A0LC14, RLME_MAGMM;  Q2W0P2, RLME_MAGSA;  
Q65TZ0, RLME_MANSM;  A1TXM4, RLME_MARHV;  Q0AQH3, RLME_MARMM;  
A6UUK5, RLME_META3;  Q8TR92, RLME_METAC;  Q0W1F9, RLME_METAR;  
A7I848, RLME_METB6;  Q466Q1, RLME_METBF;  Q12WR3, RLME_METBU;  
Q607B2, RLME_METCA;  Q1H387, RLME_METFK;  Q2FNX6, RLME_METHJ;  
Q58771, RLME_METJA;  A2SSW7, RLME_METLZ;  A4FYM2, RLME_METM5;  
A9A6B9, RLME_METM6;  A6VJR0, RLME_METM7;  Q8PUP4, RLME_METMA;  
A3CVJ3, RLME_METMJ;  Q6LZL8, RLME_METMP;  B8GG79, RLME_METPE;  
A2SF90, RLME_METPP;  A5UKI5, RLME_METS3;  Q2NHD6, RLME_METST;  
O27801, RLME_METTH;  A0B8A1, RLME_METTP;  A6USA0, RLME_METVS;  
Q1D841, RLME_MYXXD;  Q3IT24, RLME_NATPD;  Q5F9L0, RLME_NEIG1;  
B4RK82, RLME_NEIG2;  A9M3N1, RLME_NEIM0;  Q9JQX5, RLME_NEIMA;  
Q7DDL2, RLME_NEIMB;  A1KT57, RLME_NEIMF;  Q2GDL7, RLME_NEOSM;  
Q0AHC6, RLME_NITEC;  Q820A2, RLME_NITEU;  Q1QKB6, RLME_NITHX;  
A9A3M9, RLME_NITMS;  Q2YBT1, RLME_NITMU;  Q3J823, RLME_NITOC;  
Q3SQN7, RLME_NITWN;  Q2GB53, RLME_NOVAD;  A6X5L4, RLME_OCHA4;  
B6JHM9, RLME_OLICO;  A1B962, RLME_PARDP;  A7HSA5, RLME_PARL1;  
B2JFN9, RLME_PARP8;  B2SZR9, RLME_PARPJ;  Q9CNJ3, RLME_PASMU;  
Q6D9B9, RLME_PECAS;  C6DKI3, RLME_PECCP;  Q4FMX1, RLME_PELUB;  
Q7MYY0, RLME_PHOLL;  Q6LUJ9, RLME_PHOPR;  Q6L1E2, RLME_PICTO;  
A1VQI6, RLME_POLNA;  Q129M4, RLME_POLSJ;  A4SXL6, RLME_POLSQ;  
B4F2B2, RLME_PROMH;  Q48E69, RLME_PSE14;  Q15VJ6, RLME_PSEA6;  
A6VCK9, RLME_PSEA7;  B7V1G4, RLME_PSEA8;  Q02FS0, RLME_PSEAB;  
P95454, RLME_PSEAE;  Q1IF51, RLME_PSEE4;  Q4KIG3, RLME_PSEF5;  
C3K267, RLME_PSEFS;  Q3IE64, RLME_PSEHT;  A4XYE8, RLME_PSEMY;  
A5W995, RLME_PSEP1;  Q3KI92, RLME_PSEPF;  B0KHY6, RLME_PSEPG;  
Q88DV0, RLME_PSEPK;  B1J262, RLME_PSEPW;  Q87WP7, RLME_PSESM;  
Q4ZNQ4, RLME_PSEU2;  A4VNP3, RLME_PSEU5;  Q4FQX1, RLME_PSYA2;  
Q1Q955, RLME_PSYCK;  A1ST38, RLME_PSYIN;  A5WCU8, RLME_PSYWF;  
B2UGQ0, RLME_RALPJ;  Q8XZ79, RLME_RALSO;  B3PQL4, RLME_RHIE6;  
Q2KC36, RLME_RHIEC;  Q1ML15, RLME_RHIL3;  Q983F8, RLME_RHILO;  
B5ZR94, RLME_RHILW;  Q92RT9, RLME_RHIME;  Q21WW8, RLME_RHOFT;  
Q2IV68, RLME_RHOP2;  Q07LH9, RLME_RHOP5;  Q6N7Q9, RLME_RHOPA;  
Q212R3, RLME_RHOPB;  Q138J5, RLME_RHOPS;  B3QFD2, RLME_RHOPT;  
Q2RXU5, RLME_RHORT;  A3PJK8, RLME_RHOS1;  Q3J2Q5, RLME_RHOS4;  
C3PMK3, RLME_RICAE;  A8GMD3, RLME_RICAH;  A8GV60, RLME_RICB8;  
Q1RHG3, RLME_RICBR;  A8EXN1, RLME_RICCK;  Q92J64, RLME_RICCN;  
Q4UKG2, RLME_RICFE;  Q9ZE00, RLME_RICPR;  C4K0Q4, RLME_RICPU;  
B0BWD8, RLME_RICRO;  A8GQZ0, RLME_RICRS;  Q68XK5, RLME_RICTY;  
Q164M8, RLME_ROSDO;  Q5LSB0, RLME_RUEPO;  Q1GHF1, RLME_RUEST;  
A1AW32, RLME_RUTMC;  Q21H48, RLME_SACD2;  B5F6U7, RLME_SALA4;  
A9MP28, RLME_SALAR;  Q57JH1, RLME_SALCH;  B5FI23, RLME_SALDC;  
B5R0H0, RLME_SALEP;  B5REP5, RLME_SALG2;  B4TJ16, RLME_SALHS;  
B4T708, RLME_SALNS;  Q5PLC1, RLME_SALPA;  A9N744, RLME_SALPB;  
C0PZ62, RLME_SALPC;  B5BGK3, RLME_SALPK;  B4TWE7, RLME_SALSV;  
Q8Z3H3, RLME_SALTI;  Q8ZLS7, RLME_SALTY;  A8G900, RLME_SERP5;  
A1S454, RLME_SHEAM;  B8E6M4, RLME_SHEB2;  A3D7L4, RLME_SHEB5;  
A6WRH7, RLME_SHEB8;  A9KZX9, RLME_SHEB9;  Q12QI9, RLME_SHEDO;  
Q086I0, RLME_SHEFN;  B0TQB0, RLME_SHEHH;  A3QGV3, RLME_SHELP;  
Q8EHM3, RLME_SHEON;  A8H748, RLME_SHEPA;  A4Y9C8, RLME_SHEPC;  
B8CKG5, RLME_SHEPW;  A0KTY8, RLME_SHESA;  A8FYS8, RLME_SHESH;  
Q0HLG9, RLME_SHESM;  Q0HXS3, RLME_SHESR;  A1RGW7, RLME_SHESW;  
B1KRR8, RLME_SHEWM;  B2U1Z8, RLME_SHIB3;  Q31W56, RLME_SHIBS;  
Q32BF4, RLME_SHIDS;  Q0T0A5, RLME_SHIF8;  P0C0S0, RLME_SHIFL;  
Q3YX62, RLME_SHISS;  C3MGQ4, RLME_SINFN;  A6U6F0, RLME_SINMW;  
Q2NW30, RLME_SODGM;  A9FQE4, RLME_SORC5;  Q1GPG3, RLME_SPHAL;  
A5VFI9, RLME_SPHWW;  B4SRA0, RLME_STRM5;  B2FKA1, RLME_STRMK;  
A0LGZ0, RLME_SYNFM;  Q9HIH4, RLME_THEAC;  Q97C13, RLME_THEVO;  
Q31HG6, RLME_THICR;  Q3SJR5, RLME_THIDA;  B8GNX9, RLME_THISH;  
C4L8Y1, RLME_TOLAT;  Q73L97, RLME_TREDE;  O83687, RLME_TREPA;  
Q8KTR0, RLME_TREPR;  B2S3S1, RLME_TREPS;  C5CKU4, RLME_VARPS;  
A1WEE7, RLME_VEREI;  A5CX75, RLME_VESOH;  A5F937, RLME_VIBC3;  
A7MZH4, RLME_VIBCB;  Q9KU87, RLME_VIBCH;  C3LSP1, RLME_VIBCM;  
Q5E7M3, RLME_VIBF1;  B5FA72, RLME_VIBFM;  Q87LZ4, RLME_VIBPA;  
B7VJI4, RLME_VIBTL;  Q8DBW7, RLME_VIBVU;  Q7MI01, RLME_VIBVY;  
Q8D2X0, RLME_WIGBR;  Q73IS9, RLME_WOLPM;  Q5GS59, RLME_WOLTR;  
Q8PLQ8, RLME_XANAC;  Q3BUR8, RLME_XANC5;  Q4UTQ4, RLME_XANC8;  
B0RTZ3, RLME_XANCB;  Q8P9Y1, RLME_XANCP;  Q2P1M0, RLME_XANOM;  
B2SUB8, RLME_XANOP;  Q5GYL7, RLME_XANOR;  A7IDJ5, RLME_XANP2;  
B2I696, RLME_XYLF2;  Q9PH52, RLME_XYLFA;  B0U1F2, RLME_XYLFM;  
Q87F66, RLME_XYLFT;  A1JIW2, RLME_YERE8;  A7FMS9, RLME_YERP3;  
Q1CC00, RLME_YERPA;  B2K2P8, RLME_YERPB;  Q8ZBB5, RLME_YERPE;  
Q1CEK6, RLME_YERPN;  A4TRJ0, RLME_YERPP;  Q66F67, RLME_YERPS;  
B1JMH7, RLME_YERPY;  Q5NQH8, RLME_ZYMMO;  

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