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ENZYME entry: EC 2.1.1.172

Accepted Name
16S rRNA (guanine(1207)-N(2))-methyltransferase.
Alternative Name(s)
M(2)G1207 methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + guanine(1207) in 16S rRNA <=> S-adenosyl-L-homocysteine + N(2)-methylguanine(1207) in 16S rRNA
Comment(s)
  • The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA.
  • The enzyme specifically methylates guanine(1207) at N(2) in 16S rRNA.
  • Formerly EC 2.1.1.52.
Cross-references
BRENDA2.1.1.172
EC2PDB2.1.1.172
ExplorEnz2.1.1.172
PRIAM enzyme-specific profiles2.1.1.172
KEGG Ligand Database for Enzyme Nomenclature2.1.1.172
IUBMB Enzyme Nomenclature2.1.1.172
IntEnz2.1.1.172
MEDLINEFind literature relating to 2.1.1.172
MetaCyc2.1.1.172
UniProtKB/Swiss-Prot
Q6FE96, RSMC_ACIAD;  B7GWT8, RSMC_ACIB3;  B2HYF8, RSMC_ACIBC;  
B0VRJ4, RSMC_ACIBS;  A3M8J9, RSMC_ACIBT;  B0V4Z1, RSMC_ACIBY;  
A3N3U3, RSMC_ACTP2;  B3GZF1, RSMC_ACTP7;  B0BU33, RSMC_ACTPJ;  
A6VMV4, RSMC_ACTSZ;  A0KPP9, RSMC_AERHH;  A4SIE3, RSMC_AERS4;  
Q0VP64, RSMC_ALCBS;  B6EL06, RSMC_ALISL;  B4S2L3, RSMC_ALTMD;  
P57413, RSMC_BUCAI;  Q8K9L5, RSMC_BUCAP;  Q89AI2, RSMC_BUCBP;  
Q057M1, RSMC_BUCCC;  Q1QUF2, RSMC_CHRSD;  A8ALZ1, RSMC_CITK8;  
Q47VN0, RSMC_COLP3;  A7MGA7, RSMC_CROS8;  A7ZVR0, RSMC_ECO24;  
B7MNC1, RSMC_ECO45;  B7LEL6, RSMC_ECO55;  Q8X510, RSMC_ECO57;  
B5Z4Q2, RSMC_ECO5E;  B7NVD9, RSMC_ECO7I;  B7MTB6, RSMC_ECO81;  
B7LXT2, RSMC_ECO8A;  B1XFI0, RSMC_ECODH;  A8A899, RSMC_ECOHS;  
A1AJP2, RSMC_ECOK1;  Q0T8U3, RSMC_ECOL5;  Q8FA64, RSMC_ECOL6;  
B1IS49, RSMC_ECOLC;  P39406, RSMC_ECOLI;  B7NH38, RSMC_ECOLU;  
B6I2Q2, RSMC_ECOSE;  B1LEH4, RSMC_ECOSM;  Q1R2D5, RSMC_ECOUT;  
A4W687, RSMC_ENT38;  B2VH94, RSMC_ERWT9;  B7LNK6, RSMC_ESCF3;  
Q7VP87, RSMC_HAEDU;  Q4QPN2, RSMC_HAEI8;  A5UBC5, RSMC_HAEIE;  
A5UFI6, RSMC_HAEIG;  P44453, RSMC_HAEIN;  Q2SJX3, RSMC_HAHCH;  
C4K8X0, RSMC_HAMD5;  Q5R049, RSMC_IDILO;  B5Y286, RSMC_KLEP3;  
A6THY6, RSMC_KLEP7;  Q65S65, RSMC_MANSM;  A1U204, RSMC_MARHV;  
A6VRG3, RSMC_MARMS;  Q9CM79, RSMC_PASMU;  Q6D984, RSMC_PECAS;  
Q7MZN0, RSMC_PHOLL;  Q6LUS5, RSMC_PHOPR;  B4EWW4, RSMC_PROMH;  
Q48MR4, RSMC_PSE14;  Q15ZS7, RSMC_PSEA6;  A6VC20, RSMC_PSEA7;  
B7V0H2, RSMC_PSEA8;  Q02G49, RSMC_PSEAB;  Q9HVG4, RSMC_PSEAE;  
Q1IEU2, RSMC_PSEE4;  Q4K6D2, RSMC_PSEF5;  Q3ILJ2, RSMC_PSEHT;  
A4XYJ7, RSMC_PSEMY;  A5VYJ3, RSMC_PSEP1;  Q3K705, RSMC_PSEPF;  
B0KNH3, RSMC_PSEPG;  Q88PT7, RSMC_PSEPK;  B1JEN3, RSMC_PSEPW;  
Q887Y4, RSMC_PSESM;  Q4ZXT0, RSMC_PSEU2;  A4VIL0, RSMC_PSEU5;  
A1SZ19, RSMC_PSYIN;  B5F512, RSMC_SALA4;  A9MRB9, RSMC_SALAR;  
Q57G51, RSMC_SALCH;  B5FTB3, RSMC_SALDC;  B5R2I6, RSMC_SALEP;  
B5R9T9, RSMC_SALG2;  B4TGY8, RSMC_SALHS;  B4T4F9, RSMC_SALNS;  
Q5PK16, RSMC_SALPA;  A9N7C4, RSMC_SALPB;  B5BL07, RSMC_SALPK;  
B4TU29, RSMC_SALSV;  Q8Z0V2, RSMC_SALTI;  Q8ZJW6, RSMC_SALTY;  
A8G9G5, RSMC_SERP5;  A1S321, RSMC_SHEAM;  A3D8E4, RSMC_SHEB5;  
A6WJH4, RSMC_SHEB8;  A9L1V0, RSMC_SHEB9;  Q12JX1, RSMC_SHEDO;  
Q088B4, RSMC_SHEFN;  B0TSU8, RSMC_SHEHH;  A3QHZ8, RSMC_SHELP;  
Q8EIL1, RSMC_SHEON;  A8H038, RSMC_SHEPA;  A4YA93, RSMC_SHEPC;  
B8CUC9, RSMC_SHEPW;  A0L0V1, RSMC_SHESA;  A8G0F9, RSMC_SHESH;  
Q0HMF0, RSMC_SHESM;  Q0HRD8, RSMC_SHESR;  A1RG35, RSMC_SHESW;  
B1KHR8, RSMC_SHEWM;  B2TZQ2, RSMC_SHIB3;  Q31SW8, RSMC_SHIBS;  
Q327M6, RSMC_SHIDS;  Q0SX40, RSMC_SHIF8;  Q820Z6, RSMC_SHIFL;  
Q3YU23, RSMC_SHISS;  Q2NW11, RSMC_SODGM;  A5F942, RSMC_VIBC3;  
A7MUT5, RSMC_VIBCB;  Q9KUA0, RSMC_VIBCH;  Q5E2W4, RSMC_VIBF1;  
B5FAM0, RSMC_VIBFM;  Q87LY1, RSMC_VIBPA;  Q8DBY0, RSMC_VIBVU;  
Q7MHY6, RSMC_VIBVY;  A1JJ89, RSMC_YERE8;  A7FMI4, RSMC_YERP3;  
Q1C153, RSMC_YERPA;  B2K3H9, RSMC_YERPB;  Q7CG56, RSMC_YERPE;  
A9R058, RSMC_YERPG;  Q1CN00, RSMC_YERPN;  A4TQK1, RSMC_YERPP;  
Q66EW9, RSMC_YERPS;  B1JL46, RSMC_YERPY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-