ENZYME entry: EC 2.1.1.174

Accepted Name
23S rRNA (guanine(1835)-N(2))-methyltransferase.
Alternative Name(s)
Ribosomal RNA large subunit methyltransferase G.
Reaction catalysed
S-adenosyl-L-methionine + guanine(1835) in 23S rRNA <=> S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S rRNA
Comment(s)
  • The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
  • The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA.
  • Formerly EC 2.1.1.52.
Cross-references
BRENDA2.1.1.174
EC2PDB2.1.1.174
ExplorEnz2.1.1.174
PRIAM enzyme-specific profiles2.1.1.174
KEGG Ligand Database for Enzyme Nomenclature2.1.1.174
IUBMB Enzyme Nomenclature2.1.1.174
IntEnz2.1.1.174
MEDLINEFind literature relating to 2.1.1.174
MetaCyc2.1.1.174
UniProtKB/Swiss-Prot
A0KHC4, RLMG_AERHH;  A4SQM2, RLMG_AERS4;  Q0VPK2, RLMG_ALCBS;  
B6EIC1, RLMG_ALISL;  B4RZB4, RLMG_ALTMD;  A8APY0, RLMG_CITK8;  
Q488Q3, RLMG_COLP3;  A7MIS8, RLMG_CROS8;  A7ZRW7, RLMG_ECO24;  
Q8XAK8, RLMG_ECO57;  B5YRC4, RLMG_ECO5E;  B1XG88, RLMG_ECODH;  
A8A4P1, RLMG_ECOHS;  A1AG02, RLMG_ECOK1;  Q0TD22, RLMG_ECOL5;  
Q8FDE5, RLMG_ECOL6;  B1IRN3, RLMG_ECOLC;  P42596, RLMG_ECOLI;  
B1LFI2, RLMG_ECOSM;  Q1R6P6, RLMG_ECOUT;  A4WER8, RLMG_ENT38;  
B2VDD5, RLMG_ERWT9;  B5XTX7, RLMG_KLEP3;  A6TEC2, RLMG_KLEP7;  
A0L9S5, RLMG_MAGMM;  Q6D9G1, RLMG_PECAS;  Q6LTZ3, RLMG_PHOPR;  
Q48DT7, RLMG_PSE14;  Q15YR1, RLMG_PSEA6;  A6VC08, RLMG_PSEA7;  
Q02G60, RLMG_PSEAB;  Q9HVH4, RLMG_PSEAE;  Q1I4K4, RLMG_PSEE4;  
Q4K5Q4, RLMG_PSEF5;  Q3IHQ6, RLMG_PSEHT;  A4XQA3, RLMG_PSEMY;  
A5W920, RLMG_PSEP1;  Q3K6H7, RLMG_PSEPF;  B0KHQ8, RLMG_PSEPG;  
Q88E20, RLMG_PSEPK;  B1J2W7, RLMG_PSEPW;  Q0EDR2, RLMG_PSESH;  
Q87WA9, RLMG_PSESM;  Q4ZNG3, RLMG_PSEU2;  A4VI28, RLMG_PSEU5;  
A1SX22, RLMG_PSYIN;  B5F6B6, RLMG_SALA4;  A9MPU2, RLMG_SALAR;  
Q57JN9, RLMG_SALCH;  B5FHV5, RLMG_SALDC;  B5QZ55, RLMG_SALEP;  
B5REH7, RLMG_SALG2;  B4TIU8, RLMG_SALHS;  B4T690, RLMG_SALNS;  
Q5PC93, RLMG_SALPA;  A9N601, RLMG_SALPB;  B5BG31, RLMG_SALPK;  
B4TVV4, RLMG_SALSV;  Q8Z3L8, RLMG_SALTI;  Q8ZLX5, RLMG_SALTY;  
A8GJW6, RLMG_SERP5;  A1S8P4, RLMG_SHEAM;  A3D130, RLMG_SHEB5;  
A6WRY2, RLMG_SHEB8;  A9L0V0, RLMG_SHEB9;  Q12K11, RLMG_SHEDO;  
Q07YH6, RLMG_SHEFN;  B0TR07, RLMG_SHEHH;  A3QH04, RLMG_SHELP;  
Q8EHW5, RLMG_SHEON;  A8H786, RLMG_SHEPA;  A4Y3Y0, RLMG_SHEPC;  
A0KTP8, RLMG_SHESA;  A8FYW7, RLMG_SHESH;  Q0HLQ7, RLMG_SHESM;  
Q0HY38, RLMG_SHESR;  A1RN12, RLMG_SHESW;  B1KD54, RLMG_SHEWM;  
B2U1T3, RLMG_SHIB3;  Q31WU9, RLMG_SHIBS;  Q32BN8, RLMG_SHIDS;  
Q0T0I4, RLMG_SHIF8;  Q821A5, RLMG_SHIFL;  Q3YXQ6, RLMG_SHISS;  
Q82N59, RLMG_STRAW;  Q9K3L9, RLMG_STRCO;  B1VMX8, RLMG_STRGG;  
A5F5X3, RLMG_VIBC3;  A7N1U8, RLMG_VIBCB;  Q9KPR9, RLMG_VIBCH;  
Q5E6X8, RLMG_VIBF1;  B5FBH8, RLMG_VIBFM;  Q87MA4, RLMG_VIBPA;  
B7VKD0, RLMG_VIBTL;  Q8DBJ8, RLMG_VIBVU;  Q7MIC5, RLMG_VIBVY;  
A1JR10, RLMG_YERE8;  A7FE15, RLMG_YERP3;  Q1C310, RLMG_YERPA;  
B2K3B8, RLMG_YERPB;  Q0WJ78, RLMG_YERPE;  A9R1N3, RLMG_YERPG;  
Q1CMJ1, RLMG_YERPN;  A4THM8, RLMG_YERPP;  Q665P6, RLMG_YERPS;  
B1JLA4, RLMG_YERPY;  

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