ENZYME entry: EC 2.1.1.198

Accepted Name
16S rRNA (cytidine(1402)-2'-O)-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA <=> S-adenosyl-L-homocysteine + 2'-O-methylcytidine(1402) in 16S rRNA
Comment(s)
  • RsmI catalyzes the 2'-O-methylation of cytidine(1402) and RsmH (EC 2.1.1.199) catalyzes the N(4)-methylation of cytidine(1402) in 16S rRNA.
  • Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
Cross-references
BRENDA2.1.1.198
EC2PDB2.1.1.198
ExplorEnz2.1.1.198
PRIAM enzyme-specific profiles2.1.1.198
KEGG Ligand Database for Enzyme Nomenclature2.1.1.198
IUBMB Enzyme Nomenclature2.1.1.198
IntEnz2.1.1.198
MEDLINEFind literature relating to 2.1.1.198
MetaCyc2.1.1.198
UniProtKB/Swiss-Prot
Q9KGL2, RSMI_BACHD;  P37544, RSMI_BACSU;  Q661J3, RSMI_BORBP;  
P57192, RSMI_BUCAI;  Q8KA29, RSMI_BUCAP;  Q89AY5, RSMI_BUCBP;  
A0RMQ7, RSMI_CAMFF;  B5Y7N9, RSMI_COPPD;  P67088, RSMI_ECO57;  
P67087, RSMI_ECOLI;  Q2NAK3, RSMI_ERYLH;  P45298, RSMI_HAEIN;  
Q9ZLS8, RSMI_HELPJ;  P56204, RSMI_HELPY;  B4U6H0, RSMI_HYDS0;  
Q053G0, RSMI_LEPBL;  B0SPB4, RSMI_LEPBP;  Q08329, RSMI_MICOL;  
P0A641, RSMI_MYCBO;  C5J6H5, RSMI_MYCCR;  P47302, RSMI_MYCGE;  
P75046, RSMI_MYCPN;  Q98RF5, RSMI_MYCPU;  P9WGW6, RSMI_MYCTO;  
P9WGW7, RSMI_MYCTU;  Q9JWJ7, RSMI_NEIMA;  Q9JXE3, RSMI_NEIMB;  
Q9CN04, RSMI_PASMU;  Q9HVZ3, RSMI_PSEAE;  Q98DM9, RSMI_RHILO;  
Q9ZCJ3, RSMI_RICPR;  Q9A186, RSMI_STRP1;  P0DF46, RSMI_STRP3;  
Q5XDL7, RSMI_STRP6;  Q8P2A6, RSMI_STRP8;  P0DF47, RSMI_STRPQ;  
P74038, RSMI_SYNY3;  Q9WZG8, RSMI_THEMA;  O83940, RSMI_TREPA;  
Q9KUD9, RSMI_VIBCH;  Q9PFV5, RSMI_XYLFA;  Q87B70, RSMI_XYLFT;  

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