ENZYME entry: EC 2.1.1.212

Accepted Name
2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + 2,4',7-trihydroxyisoflavanone <=> S-adenosyl-L-homocysteine + 2,7-dihydroxy-4'-methoxyisoflavanone
Comment(s)
  • Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position.
  • No activity with isoflavones.
  • The enzyme is involved in formononetin biosynthesis in legumes.
  • The protein from pea (Pisum sativum) also methylates (+)- 6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270).
Cross-references
BRENDA2.1.1.212
EC2PDB2.1.1.212
ExplorEnz2.1.1.212
PRIAM enzyme-specific profiles2.1.1.212
KEGG Ligand Database for Enzyme Nomenclature2.1.1.212
IUBMB Enzyme Nomenclature2.1.1.212
IntEnz2.1.1.212
MEDLINEFind literature relating to 2.1.1.212
MetaCyc2.1.1.212
UniProtKB/Swiss-Prot
Q84KK6, I4OMT_GLYEC;  Q84KK4, I4OMT_LOTJA;  Q29U70, I4OMT_MEDTR;  

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