ENZYME entry: EC 2.1.1.262

Accepted Name
Squalene methyltransferase.
Reaction catalysed
2 S-adenosyl-L-methionine + squalene <=> 2 S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
Comment(s)
  • Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22.
  • TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form.
Cross-references
BRENDA2.1.1.262
EC2PDB2.1.1.262
ExplorEnz2.1.1.262
PRIAM enzyme-specific profiles2.1.1.262
KEGG Ligand Database for Enzyme Nomenclature2.1.1.262
IUBMB Enzyme Nomenclature2.1.1.262
IntEnz2.1.1.262
MEDLINEFind literature relating to 2.1.1.262
MetaCyc2.1.1.262
UniProtKB/Swiss-Prot
H2E7T5, SQMT1_BOTBR;  H2E7T6, SQMT2_BOTBR;  

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