ENZYME entry: EC 2.1.1.287

Accepted Name
25S rRNA (adenine(645)-N(1))-methyltransferase.
Alternative Name(s)
25S rRNA m(1)A(645) methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + adenine(645) in 25S rRNA <=> S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA
Comment(s)
  • The enzyme is found in eukaryotes.
  • The adenine position refers to tRNA the yeast Saccharomyces cerevisiae, in which the enzyme is important for ribosome biogenesis.
Cross-references
BRENDA2.1.1.287
EC2PDB2.1.1.287
ExplorEnz2.1.1.287
PRIAM enzyme-specific profiles2.1.1.287
KEGG Ligand Database for Enzyme Nomenclature2.1.1.287
IUBMB Enzyme Nomenclature2.1.1.287
IntEnz2.1.1.287
MEDLINEFind literature relating to 2.1.1.287
MetaCyc2.1.1.287
UniProtKB/Swiss-Prot
Q10257, RRP8_SCHPO;  P38961, RRP8_YEAST;  

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