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ENZYME entry: EC

Accepted Name
Carminomycin 4-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + carminomycin <=> S-adenosyl-L-homocysteine + daunorubicin
  • The enzymes from the Gram-positive bacteria Streptomyces sp. C5 and Streptomyces peucetius are involved in the biosynthesis of the anthracycline daunorubicin.
  • In vitro the enzyme from Streptomyces sp. C5 also catalyzes the 4-O- methylation of 13-dihydrocarminomycin, rhodomycin D and 10-carboxy- 13-deoxycarminomycin.
PRIAM enzyme-specific profiles2.1.1.292
KEGG Ligand Database for Enzyme Nomenclature2.1.1.292
IUBMB Enzyme Nomenclature2.1.1.292
MEDLINEFind literature relating to
Q06528, DNRK_STRPE;  Q55216, DNRK_STRS5;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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