ENZYME entry: EC 2.1.1.56

Accepted Name
mRNA (guanine-N(7)-)-methyltransferase.
Alternative Name(s)
Guanine-7-methyltransferase.
Messenger ribonucleate guanine 7-methyltransferase.
Messenger RNA guanine 7-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + G(5')pppR-RNA <=> S-adenosyl-L-homocysteine + m(7)G(5')pppR-RNA
Comment(s)
  • Adds an N(7)-methylguanine cap to mRNA.
  • The nucleoside next to the terminal guanosine may be either guanosine or adenosine.
Cross-references
BRENDA2.1.1.56
EC2PDB2.1.1.56
ExplorEnz2.1.1.56
PRIAM enzyme-specific profiles2.1.1.56
KEGG Ligand Database for Enzyme Nomenclature2.1.1.56
IUBMB Enzyme Nomenclature2.1.1.56
IntEnz2.1.1.56
MEDLINEFind literature relating to 2.1.1.56
MetaCyc2.1.1.56
UniProtKB/Swiss-Prot
P11079, LMBD2_REOVD;  Q91RA4, LMBD2_REOVJ;  Q91RA6, LMBD2_REOVL;  
Q9QSP0, L_ABLVB;  Q8JTG9, L_ABLVH;  Q2Y2L8, L_AMPV1;  
Q9E784, L_BEFVB;  O91940, L_BRSVA;  P24658, L_CDVO;  
P13179, L_CHAV;  Q6DN67, L_CPSVP;  C6S3N3, L_DMSVA;  
A4UHQ2, L_EBLV1;  A4UHQ7, L_EBLV2;  Q91DD4, L_EBORE;  
Q8JPX5, L_EBORR;  Q66802, L_EBOSM;  Q5XX01, L_EBOSU;  
Q6V1Q2, L_EBOZ5;  Q05318, L_EBOZM;  O89344, L_HENDH;  
Q77SJ8, L_HIRRV;  Q6WB93, L_HMPVC;  P20894, L_HRSV;  
P28887, L_HRSVA;  O36635, L_HRSVB;  Q9IWW8, L_HRSVL;  
Q82707, L_IHNVO;  Q82685, L_IHNVW;  Q5K2K3, L_ISFV;  
Q8B0U2, L_LBVAV;  Q4W382, L_LNYV3;  Q1PD54, L_MABVA;  
P31352, L_MABVM;  Q6UY63, L_MABVO;  P35262, L_MABVP;  
Q1PDC4, L_MABVR;  P35975, L_MEASA;  Q9WMB3, L_MEASC;  
P12576, L_MEASE;  Q8BCV9, L_MILVL;  Q6E0W6, L_MMVR;  
P0C568, L_MOKV;  Q50EW2, L_MPV15;  P30929, L_MUMPM;  
P11205, L_NDVB;  Q9DLD3, L_NDVB1;  Q997F0, L_NIPAV;  
P35946, L_PHODV;  P26676, L_PI2HT;  P12577, L_PI3H4;  
Q88434, L_PIV5;  Q03396, L_PIV5W;  Q4F8Z9, L_RABVA;  
Q66T60, L_RABVB;  Q0GBX5, L_RABVD;  A3F5L9, L_RABVE;  
Q8B6J5, L_RABVH;  A3RM23, L_RABVI;  Q9IPJ5, L_RABVN;  
P11213, L_RABVP;  Q0GBY0, L_RABVR;  P16289, L_RABVS;  
P41357, L_RINDR;  O10378, L_RYSV;  Q9DUD8, L_SENDA;  
P06829, L_SENDE;  Q06996, L_SENDF;  O55528, L_SENDO;  
P06447, L_SENDZ;  Q9QJT4, L_SHRV;  P35341, L_SV41;  
Q91DR9, L_SVCV;  P31332, L_SYNV;  Q5GA85, L_TAVCV;  
D8V078, L_TIBVC;  Q4VKV2, L_TUPVT;  P03523, L_VSIVA;  
Q8B0H0, L_VSIVC;  Q98776, L_VSIVM;  Q8B0I0, L_VSIVN;  
Q8B0H5, L_VSIVS;  P13615, L_VSNJH;  P16379, L_VSNJO;  
Q8V2R8, MCEL_CAMPM;  Q775U0, MCEL_CAMPS;  Q8QMV9, MCEL_CWPXB;  
Q80DX6, MCEL_CWPXG;  Q9J584, MCEL_FOWPN;  P25950, MCEL_RFVKA;  
O57209, MCEL_VACCA;  P20979, MCEL_VACCC;  Q9JFA8, MCEL_VACCT;  
P04298, MCEL_VACCW;  P33057, MCEL_VAR67;  Q9LHQ7, MCES1_ARATH;  
Q6Z9U7, MCES1_ORYSJ;  Q5HZ60, MCES2_ARATH;  Q6K833, MCES2_ORYSJ;  
Q754U7, MCES_ASHGO;  A1CT57, MCES_ASPCL;  Q4WN42, MCES_ASPFU;  
A2QVS9, MCES_ASPNC;  Q2UM19, MCES_ASPOR;  Q61E36, MCES_CAEBR;  
Q9XVS1, MCES_CAEEL;  Q5ADX5, MCES_CANAL;  Q6FML4, MCES_CANGA;  
P0CO65, MCES_CRYNB;  P0CO64, MCES_CRYNJ;  Q1MTD3, MCES_DANRE;  
Q6BMH4, MCES_DEBHA;  Q9VJQ4, MCES_DROME;  Q8SR66, MCES_ENCCU;  
O72908, MCES_FOWPN;  O43148, MCES_HUMAN;  Q6CKI0, MCES_KLULA;  
A5E032, MCES_LODEL;  Q4R7K1, MCES_MACFA;  A4R8D7, MCES_MAGO7;  
Q9D0L8, MCES_MOUSE;  A1DMG9, MCES_NEOFI;  A5DDJ4, MCES_PICGU;  
A3GEV2, MCES_PICST;  Q5U2U7, MCES_RAT;  O74880, MCES_SCHPO;  
Q08512, MCES_SWPVK;  Q9I8S2, MCES_XENLA;  Q28FT4, MCES_XENTR;  
Q6CC11, MCES_YARLI;  P32783, MCES_YEAST;  Q9QB92, MCES_YMTV5;  
P32094, MCE_ASFB7;  P0C995, MCE_ASFK5;  Q65216, MCE_ASFM2;  
P0C993, MCE_ASFP4;  P0C994, MCE_ASFWA;  Q5UQX1, MCE_MIMIV;  
P27909, POLG_DEN1B;  P33478, POLG_DEN1S;  P17763, POLG_DEN1W;  
P29990, POLG_DEN26;  P29991, POLG_DEN27;  P14337, POLG_DEN28;  
P07564, POLG_DEN2J;  P14340, POLG_DEN2N;  P12823, POLG_DEN2P;  
Q9WDA6, POLG_DEN2Q;  Q99D35, POLG_DEN3C;  Q5UB51, POLG_DEN3I;  
Q6YMS3, POLG_DEN3M;  P27915, POLG_DEN3P;  Q6YMS4, POLG_DEN3S;  
P09866, POLG_DEN4D;  Q2YHF2, POLG_DEN4H;  Q58HT7, POLG_DEN4P;  
Q5UCB8, POLG_DEN4S;  Q2YHF0, POLG_DEN4T;  P27395, POLG_JAEV1;  
P19110, POLG_JAEV5;  P32886, POLG_JAEVJ;  P14335, POLG_KUNJM;  
P29837, POLG_LANVT;  P22338, POLG_LIV;  P33515, POLG_MCFA;  
P05769, POLG_MVEV5;  Q04538, POLG_POWVL;  P09732, POLG_STEVM;  
Q01299, POLG_TBEVH;  P07720, POLG_TBEVS;  P14336, POLG_TBEVW;  
P06935, POLG_WNV;  P03314, POLG_YEFV1;  Q6DV88, POLG_YEFVA;  
Q6J3P1, POLG_YEFVC;  Q074N0, POLG_YEFVE;  Q89277, POLG_YEFVF;  
Q98803, POLG_YEFVI;  Q1X881, POLG_YEFVN;  Q9YRV3, POLG_YEFVT;  
Q1X880, POLG_YEFVU;  Q32ZE1, POLG_ZIKV;  Q8VA43, VP1_AQRVA;  
Q8JU62, VP1_AQRVC;  B2BND9, VP1_AQRVG;  O56043, VP2_RRSVT;  
Q9INI4, VP3_BAVJK;  Q7TDB4, VP3_MYRV9;  Q3ZK57, VP3_ROT41;  
B1NKR5, VP3_ROTAD;  A9Q1K9, VP3_ROTB2;  A7J3A0, VP3_ROTBN;  
Q65526, VP3_ROTBS;  Q6WAT6, VP3_ROTBU;  Q6WNV6, VP3_ROTCC;  
Q6WNV7, VP3_ROTEL;  A4ZCW6, VP3_ROTH3;  Q6WNW3, VP3_ROTH6;  
B1NKR1, VP3_ROTH7;  Q82041, VP3_ROTHC;  Q6WNW5, VP3_ROTHD;  
Q9QNB1, VP3_ROTHK;  B1NKS7, VP3_ROTHL;  B1NKT1, VP3_ROTHP;  
A7J392, VP3_ROTHS;  B1NKT9, VP3_ROTHT;  Q91HJ9, VP3_ROTHU;  
Q6WVH5, VP3_ROTHW;  Q45UF7, VP3_ROTJ1;  Q6WNV8, VP3_ROTP5;  
P26192, VP3_ROTPC;  Q8BB04, VP3_ROTRF;  P15736, VP3_ROTS1;  
A2T3S5, VP3_ROTSH;  B3F2X7, VP3_ROTTU;  B2BMF9, VP3_ROTW3;  
B1NKU3, VP3_ROTWI;  A7J3A4, VP3_ROTYO;  Q91ID8, VP4_LDCPR;  
Q2Y0E6, VP5_APRVF;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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