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ENZYME entry: EC 2.4.1.144

Accepted Name
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase.
Alternative Name(s)
Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase.
GnTIII.
N-acetylglucosaminyltransferase III.
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III.
Uridine diphosphoacetylglucosamine-glycopeptide beta-4- acetylglucosaminyltransferase III.
Reaction catalysed
UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R <=> UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R
Comment(s)
  • R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.
  • The action of this enzyme probably prevents further attachment of N-acetylglucosamine residues to the growing carbohydrate chain.
  • Formerly EC 2.4.1.51.
Cross-references
BRENDA2.4.1.144
EC2PDB2.4.1.144
ExplorEnz2.4.1.144
PRIAM enzyme-specific profiles2.4.1.144
KEGG Ligand Database for Enzyme Nomenclature2.4.1.144
IUBMB Enzyme Nomenclature2.4.1.144
IntEnz2.4.1.144
MEDLINEFind literature relating to 2.4.1.144
MetaCyc2.4.1.144
UniProtKB/Swiss-Prot
Q09327, MGAT3_HUMAN;  Q10470, MGAT3_MOUSE;  Q02527, MGAT3_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-