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ENZYME entry: EC

Accepted Name
O-acetylhomoserine aminocarboxypropyltransferase.
Alternative Name(s)
Methionine synthase.
O-acetyl-L-homoserine acetate-lyase (adding methanethiol).
O-acetyl-L-homoserine sulfhydrolase.
O-acetylhomoserine (thiol)-lyase.
O-acetylhomoserine sulfhydrolase.
OAH sulfhydrylase.
Reaction catalysed
O-acetyl-L-homoserine + methanethiol <=> L-methionine + acetate
  • Also reacts with other thiols and H(2)S, producing homocysteine or thioethers.
  • The name methionine synthase is more commonly applied to EC
  • The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC, but more slowly.
  • Formerly EC
PRIAM enzyme-specific profiles2.5.1.49
KEGG Ligand Database for Enzyme Nomenclature2.5.1.49
IUBMB Enzyme Nomenclature2.5.1.49
MEDLINEFind literature relating to
P50125, CYSD_EMENI;  Q92441, CYSD_KLULA;  O13326, CYSD_SCHPO;  
P06106, CYSD_YEAST;  

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