ENZYME entry: EC 2.6.1.85
| Accepted Name |
|---|
| Aminodeoxychorismate synthase.
|
| Alternative Name(s) |
|---|
| 4-amino-4-deoxychorismate synthase. |
| ADC synthase. |
| Reaction catalysed |
|---|
| Chorismate + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
- Composed of two subunits, PabA and PabB.
- In the absence of PabA and glutamine, PabB converts ammonia and
chorismate into 4-amino-4-deoxychorismate.
- PabA converts glutamine into glutamate only in the presence of
stoichiometric amounts of PabB.
- Coupled with EC 4.1.3.38, to form 4-aminobenzoate.
- Formerly EC 6.3.5.8.
|
| Cross-references |
|---|
| PROSITE | PDOC00948 |
| BRENDA | 2.6.1.85 |
| EC2PDB | 2.6.1.85 |
| ExplorEnz | 2.6.1.85 |
| PRIAM enzyme-specific profiles | 2.6.1.85 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.85 |
| IUBMB Enzyme Nomenclature | 2.6.1.85 |
| IntEnz | 2.6.1.85 |
| MEDLINE | Find literature relating to 2.6.1.85 |
| MetaCyc | 2.6.1.85 |
| UniProtKB/Swiss-Prot |
| P28819, PABA_BACSU; | P00903, PABA_ECOLI; | P06194, PABA_ENTAE; |
| P06193, PABA_SALTY; | P06195, PABA_SERMA; | P27627, PABA_STRLI; |
| P28820, PABB_BACSU; | P05041, PABB_ECOLI; | P12679, PABB_ENTAE; |
| P27629, PABB_LACLL; | P12680, PABB_SALTY; | P27630, PABB_STRLI; |
| O94277, PABS_SCHPO; | P32483, PABS_STRGR; | P37254, PABS_YEAST; |
|
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