ENZYME entry: EC 2.7.11.27

Accepted Name
[Acetyl-CoA carboxylase] kinase.
Alternative Name(s)
Acetyl coenzyme A carboxylase kinase (phosphorylating).
Acetyl-CoA carboxylase bound kinase.
Acetyl-CoA carboxylase kinase.
Acetyl-CoA carboxylase kinase (AMP-activated).
Acetyl-CoA carboxylase kinase (cAMP-independent).
Acetyl-coenzyme A carboxylase kinase.
AMPK.
I-peptide kinase.
Reaction catalysed
ATP + [acetyl-CoA carboxylase] <=> ADP + [acetyl-CoA carboxylase] phosphate
Comment(s)
  • Phosphorylates and inactivates EC 6.4.1.2, which can be dephosphorylated and reactivated by EC 3.1.3.17.
  • More active toward the dimeric form of acetyl-CoA carboxylase than the polymeric form.
  • Phosphorylates serine residues.
  • Formerly EC 2.7.1.111 and EC 2.7.1.128.
Cross-references
BRENDA2.7.11.27
EC2PDB2.7.11.27
ExplorEnz2.7.11.27
PRIAM enzyme-specific profiles2.7.11.27
KEGG Ligand Database for Enzyme Nomenclature2.7.11.27
IUBMB Enzyme Nomenclature2.7.11.27
IntEnz2.7.11.27
MEDLINEFind literature relating to 2.7.11.27
MetaCyc2.7.11.27
UniProtKB/Swiss-Prot
Q13131, AAPK1_HUMAN;  Q5EG47, AAPK1_MOUSE;  Q09136, AAPK1_PIG;  
Q5RDH5, AAPK1_PONAB;  P54645, AAPK1_RAT;  P54646, AAPK2_HUMAN;  
Q8BRK8, AAPK2_MOUSE;  Q28948, AAPK2_PIG;  Q5RD00, AAPK2_PONAB;  
Q09137, AAPK2_RAT;  

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