ENZYME entry: EC 2.7.11.5

Accepted Name
[Isocitrate dehydrogenase (NADP(+))] kinase.
Alternative Name(s)
ICDH kinase/phosphatase.
IDH kinase.
IDH kinase/phosphatase.
IDH-K/P.
IDHK/P.
Isocitrate dehydrogenase kinase.
Isocitrate dehydrogenase kinase (phosphorylating).
Isocitrate dehydrogenase kinase/phosphatase.
Reaction catalysed
ATP + [isocitrate dehydrogenase (NADP(+))] <=> ADP + [isocitrate dehydrogenase (NADP(+))] phosphate
Comment(s)
  • Has no activating compound but is specific for its substrate.
  • Phosphorylates and inactivates EC 1.1.1.42.
  • Formerly EC 2.7.1.116.
Cross-references
BRENDA2.7.11.5
EC2PDB2.7.11.5
ExplorEnz2.7.11.5
PRIAM enzyme-specific profiles2.7.11.5
KEGG Ligand Database for Enzyme Nomenclature2.7.11.5
IUBMB Enzyme Nomenclature2.7.11.5
IntEnz2.7.11.5
MEDLINEFind literature relating to 2.7.11.5
MetaCyc2.7.11.5
UniProtKB/Swiss-Prot
Q3IKY9, ACEK1_PSEHT;  Q3IHD9, ACEK2_PSEHT;  A1TVC1, ACEK_ACIAC;  
A1WCB1, ACEK_ACISJ;  A0KMM4, ACEK_AERHH;  A4SQ71, ACEK_AERS4;  
Q2IJI0, ACEK_ANADE;  A7HB82, ACEK_ANADF;  Q5P801, ACEK_AROAE;  
A1K4K7, ACEK_AZOSB;  Q7WDP2, ACEK_BORBR;  Q7W2P4, ACEK_BORPA;  
B1YNR4, ACEK_BURA4;  Q1BT42, ACEK_BURCA;  B1JZD3, ACEK_BURCC;  
A0KAZ7, ACEK_BURCH;  Q0BBE2, ACEK_BURCM;  A9AE52, ACEK_BURM1;  
A3MNH1, ACEK_BURM7;  A2S7Q4, ACEK_BURM9;  Q62MX7, ACEK_BURMA;  
A1V827, ACEK_BURMS;  A3NQT1, ACEK_BURP0;  Q3JWQ8, ACEK_BURP1;  
A3N530, ACEK_BURP6;  B2JKI4, ACEK_BURP8;  B2SWU4, ACEK_BURPP;  
Q63Y16, ACEK_BURPS;  Q39CF3, ACEK_BURS3;  Q2T1P5, ACEK_BURTA;  
A4JIA9, ACEK_BURVG;  Q146J2, ACEK_BURXL;  A8ANB7, ACEK_CITK8;  
Q487A4, ACEK_COLP3;  A7MPD7, ACEK_CROS8;  Q8KLU8, ACEK_CUPNH;  
Q477B5, ACEK_CUPPJ;  B2AG85, ACEK_CUPTR;  Q47BD0, ACEK_DECAR;  
A7ZUN0, ACEK_ECO24;  B7UPG7, ACEK_ECO27;  B7MIZ8, ACEK_ECO45;  
B7LAV8, ACEK_ECO55;  Q8X607, ACEK_ECO57;  B5Z0A8, ACEK_ECO5E;  
B7N2L5, ACEK_ECO81;  B7M7S1, ACEK_ECO8A;  C5A0V3, ACEK_ECOBW;  
B1XC15, ACEK_ECODH;  A8A7B3, ACEK_ECOHS;  A1AII6, ACEK_ECOK1;  
Q0TA53, ACEK_ECOL5;  Q8FB61, ACEK_ECOL6;  B1IUN6, ACEK_ECOLC;  
P11071, ACEK_ECOLI;  B7NFV2, ACEK_ECOLU;  B6I5M4, ACEK_ECOSE;  
B1LPH3, ACEK_ECOSM;  Q1R3T1, ACEK_ECOUT;  A4W5D0, ACEK_ENT38;  
B7LKA4, ACEK_ESCF3;  Q5QWZ3, ACEK_IDILO;  B5XYC7, ACEK_KLEP3;  
A6TGR8, ACEK_KLEP7;  A2SL82, ACEK_METPP;  Q6D012, ACEK_PECAS;  
C6DFQ3, ACEK_PECCP;  Q7MZA0, ACEK_PHOLL;  Q6LUQ1, ACEK_PHOPR;  
A1VJF1, ACEK_POLNA;  Q124G2, ACEK_POLSJ;  Q15XV2, ACEK_PSEA6;  
A6V8H8, ACEK_PSEA7;  B7UVK3, ACEK_PSEA8;  Q02JM4, ACEK_PSEAB;  
Q9I3W8, ACEK_PSEAE;  Q1I6M7, ACEK_PSEE4;  Q4KGH6, ACEK_PSEF5;  
A4XT90, ACEK_PSEMY;  A5W024, ACEK_PSEP1;  Q3KGE4, ACEK_PSEPF;  
B0KS44, ACEK_PSEPG;  Q88EA1, ACEK_PSEPK;  B1JCS1, ACEK_PSEPW;  
A4VMC4, ACEK_PSEU5;  Q1LS86, ACEK_RALME;  B2UDV1, ACEK_RALPJ;  
Q8Y2Q7, ACEK_RALSO;  Q21RR4, ACEK_RHOFT;  Q2J2X6, ACEK_RHOP2;  
Q6NCX0, ACEK_RHOPA;  Q13E74, ACEK_RHOPS;  B3Q986, ACEK_RHOPT;  
B5F1J4, ACEK_SALA4;  Q57H42, ACEK_SALCH;  B5FQM6, ACEK_SALDC;  
B5QYG6, ACEK_SALEP;  B5R7Q4, ACEK_SALG2;  B4TDG1, ACEK_SALHS;  
B4T1M4, ACEK_SALNS;  A9N0M7, ACEK_SALPB;  C0Q489, ACEK_SALPC;  
B4TQM3, ACEK_SALSV;  Q8Z1V8, ACEK_SALTI;  P51067, ACEK_SALTY;  
A8GKF5, ACEK_SERP5;  B2TWJ8, ACEK_SHIB3;  Q31TY7, ACEK_SHIBS;  
Q328N5, ACEK_SHIDS;  Q8PFZ0, ACEK_XANAC;  Q3BNH4, ACEK_XANC5;  
Q4UPY1, ACEK_XANC8;  B0RWU0, ACEK_XANCB;  Q8P4D0, ACEK_XANCP;  
A1JRX0, ACEK_YERE8;  A7FDG2, ACEK_YERP3;  Q1CC34, ACEK_YERPA;  
Q8ZAR7, ACEK_YERPE;  A9R541, ACEK_YERPG;  Q1CNT1, ACEK_YERPN;  
A4TH34, ACEK_YERPP;  Q664W4, ACEK_YERPS;  

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