ENZYME entry: EC 2.7.2.4

Accepted Name
Aspartate kinase.
Alternative Name(s)
Aspartokinase.
Reaction catalysed
ATP + L-aspartate <=> ADP + 4-phospho-L-aspartate
Comment(s)
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3.
  • This is also the case for two of the four isoenzymes in Arabidopsis thaliana.
  • The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
Cross-references
PROSITEPDOC00289
BRENDA2.7.2.4
EC2PDB2.7.2.4
ExplorEnz2.7.2.4
PRIAM enzyme-specific profiles2.7.2.4
KEGG Ligand Database for Enzyme Nomenclature2.7.2.4
IUBMB Enzyme Nomenclature2.7.2.4
IntEnz2.7.2.4
MEDLINEFind literature relating to 2.7.2.4
MetaCyc2.7.2.4
UniProtKB/Swiss-Prot
P00561, AK1H_ECOLI;  P27725, AK1H_SERMA;  Q9LYU8, AK1_ARATH;  
Q04795, AK1_BACSU;  P00562, AK2H_ECOLI;  O23653, AK2_ARATH;  
P08495, AK2_BACSU;  Q9S702, AK3_ARATH;  P94417, AK3_BACSU;  
P08660, AK3_ECOLI;  Q9SA18, AKH1_ARATH;  P49079, AKH1_MAIZE;  
O81852, AKH2_ARATH;  P49080, AKH2_MAIZE;  P57290, AKH_BUCAI;  
Q8K9U9, AKH_BUCAP;  Q89AR4, AKH_BUCBP;  P37142, AKH_DAUCA;  
P44505, AKH_HAEIN;  O67221, AK_AQUAE;  Q59229, AK_BACSG;  
Q9PK32, AK_CHLMU;  Q9Z6L0, AK_CHLPN;  O84367, AK_CHLTR;  
Q8RQN1, AK_COREF;  P41398, AK_CORFL;  P26512, AK_CORGL;  
P53553, AK_GEOSE;  Q9ZJZ7, AK_HELPJ;  O25827, AK_HELPY;  
Q57991, AK_METJA;  P0A4Z9, AK_MYCBO;  P41403, AK_MYCSM;  
P9WPX2, AK_MYCTO;  P9WPX3, AK_MYCTU;  O69077, AK_PSEAE;  
Q1RGM9, AK_RICBR;  Q92GF9, AK_RICCN;  Q4UK84, AK_RICFE;  
Q9ZCI7, AK_RICPR;  Q68VZ7, AK_RICTY;  O60163, AK_SCHPO;  
P61488, AK_THET2;  P61489, AK_THETH;  P10869, AK_YEAST;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-