ENZYME entry: EC 1.1.1.3

Accepted Name
Homoserine dehydrogenase.
Reaction catalysed
L-homoserine + NAD(P)(+) <=> L-aspartate 4-semialdehyde + NAD(P)H
Comment(s)
  • The enzyme from Saccharomyces cerevisiae acts most rapidly with NAD(+); the Neurospora enzyme with NADP(+).
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 2.7.2.4.
Cross-references
PROSITEPDOC00800
BRENDA1.1.1.3
EC2PDB1.1.1.3
ExplorEnz1.1.1.3
PRIAM enzyme-specific profiles1.1.1.3
KEGG Ligand Database for Enzyme Nomenclature1.1.1.3
IUBMB Enzyme Nomenclature1.1.1.3
IntEnz1.1.1.3
MEDLINEFind literature relating to 1.1.1.3
MetaCyc1.1.1.3
UniProtKB/Swiss-Prot
P00561, AK1H_ECOLI;  P27725, AK1H_SERMA;  P00562, AK2H_ECOLI;  
Q9SA18, AKH1_ARATH;  P49079, AKH1_MAIZE;  O81852, AKH2_ARATH;  
P49080, AKH2_MAIZE;  P57290, AKH_BUCAI;  Q8K9U9, AKH_BUCAP;  
Q89AR4, AKH_BUCBP;  P37142, AKH_DAUCA;  P44505, AKH_HAEIN;  
P19582, DHOM_BACSU;  P08499, DHOM_CORGL;  Q5B998, DHOM_EMENI;  
Q9ZL20, DHOM_HELPJ;  P56429, DHOM_HELPY;  Q9CGD8, DHOM_LACLA;  
P52985, DHOM_LACLC;  P37143, DHOM_METGL;  Q58997, DHOM_METJA;  
P63630, DHOM_MYCBO;  P46806, DHOM_MYCLE;  P63629, DHOM_MYCTU;  
P29365, DHOM_PSEAE;  O94671, DHOM_SCHPO;  P52986, DHOM_SYNY3;  
P31116, DHOM_YEAST;  P37144, DHON_METGL;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-