To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.7.7.2

Accepted Name
FAD synthetase.
Alternative Name(s)
FAD diphosphorylase.
FAD pyrophosphorylase.
FADS.
Flavin adenine dinucleotide synthetase.
FMN adenylyltransferase.
Reaction catalysed
ATP + FMN <=> diphosphate + FAD
Cofactor(s)
Mg(2+).
Comment(s)
  • Highly specific for ATP as phosphate donor.
  • The cofactors FMN and FAD participate in numerous processes in all organisms, including mitochondrial electron transport, photosynthesis, fatty-acid oxidation, and metabolism of vitamin B6, vitamin B12 and folates.
  • While monofunctional FAD synthetase is found in eukaryotes and in some prokaryotes, most prokaryotes have a bifunctional enzyme that exhibits both this activity and that of EC 2.7.1.26.
Cross-references
BRENDA2.7.7.2
EC2PDB2.7.7.2
ExplorEnz2.7.7.2
PRIAM enzyme-specific profiles2.7.7.2
KEGG Ligand Database for Enzyme Nomenclature2.7.7.2
IUBMB Enzyme Nomenclature2.7.7.2
IntEnz2.7.7.2
MEDLINEFind literature relating to 2.7.7.2
MetaCyc2.7.7.2
UniProtKB/Swiss-Prot
Q626I0, FAD1_CAEBR;  Q22017, FAD1_CAEEL;  Q68EH8, FAD1_DANRE;  
Q8NFF5, FAD1_HUMAN;  Q8R123, FAD1_MOUSE;  Q5RCH4, FAD1_PONAB;  
O74841, FAD1_SCHPO;  P38913, FAD1_YEAST;  Q6ING7, FLAD1_XENLA;  
Q7NBZ0, MNMA_MYCGA;  P54575, RIBC_BACSU;  Q9FMW8, RIBF1_ARATH;  
Q8VZR0, RIBF2_ARATH;  P57250, RIBF_BUCAI;  Q8K9Z1, RIBF_BUCAP;  
Q59263, RIBF_CORAM;  P0AG42, RIBF_ECO57;  P0AG41, RIBF_ECOL6;  
P0AG40, RIBF_ECOLI;  A4IT50, RIBF_GEOTN;  P44957, RIBF_HAEIN;  
P47391, RIBF_MYCGE;  P75587, RIBF_MYCPN;  Q10BX9, RIBF_ORYSJ;  
P22990, RIBF_PSEFL;  O84990, RIBF_RHOOP;  P0AG43, RIBF_SHIFL;  
P73651, RIBF_SYNY3;  B5I9H4, RIBL_ACIB4;  O28854, RIBL_ARCFU;  
D2RES5, RIBL_ARCPA;  D3RZA9, RIBL_FERPA;  D8J4S4, RIBL_HALJB;  
B9LSN4, RIBL_HALLT;  C7P4K0, RIBL_HALMD;  B0R450, RIBL_HALS3;  
Q9HRB2, RIBL_HALSA;  D2RTP8, RIBL_HALTV;  C7NTR1, RIBL_HALUD;  
D4GVJ2, RIBL_HALVD;  B1L7J8, RIBL_KORCO;  A6UWK8, RIBL_META3;  
Q8TPT5, RIBL_METAC;  Q0W933, RIBL_METAR;  A7I4S0, RIBL_METB6;  
Q46AS7, RIBL_METBF;  Q12YR1, RIBL_METBU;  D7E8Z9, RIBL_METEZ;  
C7P607, RIBL_METFA;  E3GWN9, RIBL_METFV;  Q2FT79, RIBL_METHJ;  
D5VUB0, RIBL_METIM;  Q58579, RIBL_METJA;  Q8TXT2, RIBL_METKA;  
A2SQH8, RIBL_METLZ;  A4FXX6, RIBL_METM5;  A9AB01, RIBL_METM6;  
A6VFN4, RIBL_METM7;  Q8Q095, RIBL_METMA;  A3CXW9, RIBL_METMJ;  
Q6LYP5, RIBL_METMP;  D5EBS7, RIBL_METMS;  E1RHM5, RIBL_METP4;  
B8GJN8, RIBL_METPE;  D1YZF2, RIBL_METPS;  D3DZ18, RIBL_METRM;  
A5ULI6, RIBL_METS3;  D3S3T0, RIBL_METSF;  Q2NHB2, RIBL_METST;  
O26932, RIBL_METTH;  D9PX81, RIBL_METTM;  A0B7A6, RIBL_METTP;  
D7DTT8, RIBL_METV3;  C9RF94, RIBL_METVM;  A6UNT3, RIBL_METVS;  
D3SYU6, RIBL_NATMM;  Q3IQ95, RIBL_NATPD;  Q6L0A7, RIBL_PICTO;  
Q9UZ37, RIBL_PYRAB;  Q8U1T9, RIBL_PYRFU;  O58466, RIBL_PYRHO;  
Q9HJ34, RIBL_THEAC;  C5A1S7, RIBL_THEGJ;  Q5JHT4, RIBL_THEKO;  
B6YXC8, RIBL_THEON;  C6A439, RIBL_THESM;  Q979C2, RIBL_THEVO;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-