To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC

Accepted Name
Bile-salt sulfotransferase.
Alternative Name(s)
Bile acid sulfotransferase I.
Bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase.
Bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase.
Glycolithocholate sulfotransferase.
Reaction catalysed
  • 3'-phosphoadenylyl sulfate + glycolithocholate <=> adenosine 3',5'-bisphosphate + glycolithocholate 3-sulfate
  • 3'-phosphoadenylyl sulfate + taurolithocholate <=> adenosine 3',5'-bisphosphate + taurolithocholate sulfate
  • The formation of sulfate esters of bile acids is an essential step in the prevention of toxicity by monohydroxy bile acids in many species.
  • This enzyme is both a bile salt and a 3-hydroxysteroid sulfotransferase.
  • In addition to the 5-beta-bile acid glycolithocholate, deoxycholate, 3-beta-hydroxy-5-cholenoate and dehydroepiandrosterone (3-beta- hydroxyandrost-5-en-17-one) also act as substrates (see also EC and EC
  • May be identical to EC
PRIAM enzyme-specific profiles2.8.2.14
KEGG Ligand Database for Enzyme Nomenclature2.8.2.14
IUBMB Enzyme Nomenclature2.8.2.14
MEDLINEFind literature relating to
Q06520, ST2A1_HUMAN;  P52842, ST2A1_MACFA;  P52843, ST2A1_MOUSE;  
P15709, ST2A1_RAT;  P50236, ST2A2_MOUSE;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-