ENZYME entry: EC 2.8.2.34

Accepted Name
Glycochenodeoxycholate sulfotransferase.
Alternative Name(s)
BAST.
Bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase.
Bile acid:PAPS:sulfotransferase.
Reaction catalysed
3'-phosphoadenylyl sulfate + glycochenodeoxycholate <=> adenosine 3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate
Comment(s)
  • Specifically sulfates glycochenodeoxycholate at the 7-alpha-position (see also EC 2.8.2.14).
  • The monohydroxy bile acids glycolithocholate, chenodeoxycholate and ursodeoxycholate act as inhibitors.
Cross-references
BRENDA2.8.2.34
EC2PDB2.8.2.34
ExplorEnz2.8.2.34
PRIAM enzyme-specific profiles2.8.2.34
KEGG Ligand Database for Enzyme Nomenclature2.8.2.34
IUBMB Enzyme Nomenclature2.8.2.34
IntEnz2.8.2.34
MEDLINEFind literature relating to 2.8.2.34
MetaCyc2.8.2.34

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