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ENZYME entry: EC 18.104.22.168
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|3'-phosphoadenylyl sulfate + 5-alpha-cholan-3-alpha,7-alpha,12-alpha,24-tetrol <=> adenosine 3',5'-bisphosphate + 5-alpha-cholan-3-alpha,7-alpha,12-alpha-triol 24-sulfate|
- The enzyme from the lamprey Petromyzon marinus can also use the
corresponding 3-ketone as a substrate.
- It is stereoselective (5-alpha-cholane) and regioselective,
exhibiting a preference for an hydroxy group at C-24.
- The enzyme is inactive when allocholic acid, which has a carboxy
group at C-24, is used as a substrate.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
entries corresponding to 2.8.2.-
entries corresponding to 2.8.-.-
entries corresponding to 2.-.-.-