ENZYME entry: EC 3.1.1.51
| Accepted Name |
|---|
| Phorbol-diester hydrolase.
|
| Alternative Name(s) |
|---|
| Diacylphorbate 12-hydrolase. |
| Reaction catalysed |
|---|
| Phorbol 12,13-dibutanoate + H(2)O <=> phorbol 13-butanoate + butanoate |
| Comment(s) |
|---|
- Hydrolyzes the 12-ester bond in a variety of 12,13-diacylphorbols
(phorbol is a diterpenoid).
- This reaction inactivates tumor promoter 12-O-tetradecanoylphorbol-
13-acetate from croton oil.
|
| Cross-references |
|---|
| BRENDA | 3.1.1.51 |
| EC2PDB | 3.1.1.51 |
| ExplorEnz | 3.1.1.51 |
| PRIAM enzyme-specific profiles | 3.1.1.51 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.51 |
| IUBMB Enzyme Nomenclature | 3.1.1.51 |
| IntEnz | 3.1.1.51 |
| MEDLINE | Find literature relating to 3.1.1.51 |
| MetaCyc | 3.1.1.51 |
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UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
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ENZYME /
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