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ENZYME entry: EC

Accepted Name
Pyrethroid hydrolase.
Alternative Name(s)
Pyrethroid-cleaving enzyme.
Pyrethroid-hydrolyzing carboxylesterase.
Pyrethroid-hydrolyzing esterase.
Pyrethroid-selective esterase.
Reaction catalysed
Trans-permethrin + H(2)O <=> (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
  • The enzyme is involved in degradation of pyrethroid pesticides.
  • The enzymes from Sphingobium sp., Klebsiella sp. and Aspergillus niger hydrolyze cis-permethrin at approximately equal rate to trans- permethrin.
  • The enzyme from mouse hydrolyzes trans-permethrin at a rate about 22-fold higher than cis-permethrin.
PRIAM enzyme-specific profiles3.1.1.88
KEGG Ligand Database for Enzyme Nomenclature3.1.1.88
IUBMB Enzyme Nomenclature3.1.1.88
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
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