ENZYME entry: EC 3.1.3.56

Accepted Name
Inositol-polyphosphate 5-phosphatase.
Alternative Name(s)
5PTase.
D-myo-inositol 1,4,5-triphosphate 5-phosphatase.
D-myo-inositol 1,4,5-trisphosphate 5-phosphatase.
D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase.
Inosine triphosphatase.
Inositol 1,4,5-trisphosphate phosphatase.
Inositol phosphate 5-phosphomonoesterase.
Inositol polyphosphate-5-phosphatase.
Inositol trisphosphate phosphomonoesterase.
Inositol-1,4,5-trisphosphate 5-phosphatase.
Inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase.
Ins(1,4,5)P(3) 5-phosphatase.
InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase.
L-myo-inositol 1,4,5-trisphosphate-monoesterase.
Myo-inositol-1,4,5-trisphosphate 5-phosphatase.
Type I inositol-polyphosphate phosphatase.
Reaction catalysed
  • D-myo-inositol 1,4,5-trisphosphate + H(2)O <=> myo-inositol 1,4-bisphosphate + phosphate
  • 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O <=> 1D-myo-inositol 1,3,4-trisphosphate + phosphate
Comment(s)
This enzyme is distinguished from the family of enzymes classified under EC 3.1.3.36 by its inability to dephosphorylate inositol lipids.
Cross-references
BRENDA3.1.3.56
EC2PDB3.1.3.56
ExplorEnz3.1.3.56
PRIAM enzyme-specific profiles3.1.3.56
KEGG Ligand Database for Enzyme Nomenclature3.1.3.56
IUBMB Enzyme Nomenclature3.1.3.56
IntEnz3.1.3.56
MEDLINEFind literature relating to 3.1.3.56
MetaCyc3.1.3.56
UniProtKB/Swiss-Prot
Q17848, I5P1_CAEEL;  Q29467, I5P1_CANFA;  Q14642, I5P1_HUMAN;  
Q9BT40, INP5K_HUMAN;  Q8C5L6, INP5K_MOUSE;  Q84MA2, IP5P1_ARATH;  
Q9FUR2, IP5P2_ARATH;  Q9LR47, IP5P3_ARATH;  Q5EAF2, IP5PB_ARATH;  
O80560, IP5PC_ARATH;  Q9SYK4, IP5PD_ARATH;  Q15735, PI5PA_HUMAN;  
P59644, PI5PA_MOUSE;  Q9JMC1, PI5PA_RAT;  

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