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ENZYME entry: EC 3.2.1.14

Accepted Name
Chitinase.
Alternative Name(s)
1,4-beta-poly-N-acetylglucosaminidase.
Chitodextrinase.
Poly-beta-glucosaminidase.
Reaction catalysed
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins
Comment(s)
  • The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act.
  • Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase.
  • Cf. EC 3.2.1.202.
Cross-references
PROSITEPDOC00620 ; PDOC00839
BRENDA3.2.1.14
EC2PDB3.2.1.14
ExplorEnz3.2.1.14
PRIAM enzyme-specific profiles3.2.1.14
KEGG Ligand Database for Enzyme Nomenclature3.2.1.14
IUBMB Enzyme Nomenclature3.2.1.14
IntEnz3.2.1.14
MEDLINEFind literature relating to 3.2.1.14
MetaCyc3.2.1.14
UniProtKB/Swiss-Prot
P11218, AGI_URTDI;  P84708, CAI_PHAVU;  Q9W5U2, CHI10_DROME;  
Q5NB11, CHI10_ORYSJ;  O74199, CHI11_METAN;  Q10S66, CHI11_ORYSJ;  
P25765, CHI12_ORYSJ;  P32470, CHI1_APHAL;  D4AT07, CHI1_ARTBC;  
Q5AAH2, CHI1_CANAL;  P46876, CHI1_CANAX;  P86078, CHI1_CAPAA;  
P86081, CHI1_CAPCH;  P29137, CHI1_CASSA;  Q1E3R8, CHI1_COCIM;  
C5P230, CHI1_COCP7;  P0CB51, CHI1_COCPS;  P85343, CHI1_GINBI;  
Q39799, CHI1_GOSHI;  P11955, CHI1_HORVU;  O14456, CHI1_METAN;  
E9ERT9, CHI1_METRA;  Q42993, CHI1_ORYSJ;  P21225, CHI1_PEA;  
H2A0L4, CHI1_PINMG;  P29025, CHI1_RHINI;  P29026, CHI1_RHIOL;  
P52403, CHI1_SOLTU;  P29115, CHI1_STROI;  P85337, CHI1_TAXBA;  
Q41596, CHI1_THECC;  P08252, CHI1_TOBAC;  Q06014, CHI2_ARAHY;  
D4AVJ0, CHI2_ARTBC;  Q09023, CHI2_BRANA;  P40953, CHI2_CANAL;  
P86079, CHI2_CAPAA;  P86082, CHI2_CAPCH;  Q1EAR5, CHI2_COCIM;  
P54197, CHI2_COCP7;  Q39785, CHI2_GOSHI;  P23951, CHI2_HORVU;  
Q4U4T0, CHI2_METAN;  E9F9R9, CHI2_METRA;  Q7DNA1, CHI2_ORYSJ;  
P21226, CHI2_PEA;  H2A0L5, CHI2_PINMG;  P29027, CHI2_RHIOL;  
P52404, CHI2_SOLTU;  P29116, CHI2_STROI;  P85338, CHI2_TAXBA;  
P24091, CHI2_TOBAC;  Q06350, CHI2_YEAST;  D4B4X4, CHI33_ARTBC;  
Q12713, CHI33_TRIHA;  Q8NJQ5, CHI37_TRIHA;  Q06015, CHI3_ARAHY;  
P40954, CHI3_CANAL;  Q6QDR4, CHI3_METAN;  E9ENC6, CHI3_METRA;  
P24626, CHI3_ORYSJ;  P52405, CHI3_SOLTU;  P85355, CHI3_TAXBA;  
P29059, CHI3_TOBAC;  P48827, CHI42_TRIHA;  A6N6J0, CHI46_TRIHA;  
Q06016, CHI4_ARAHY;  Q06209, CHI4_BRANA;  Q5AM60, CHI4_CANAL;  
C9WJD0, CHI4_METAN;  E9F7R6, CHI4_METRA;  O04138, CHI4_ORYSJ;  
P27054, CHI4_PHAVU;  P52406, CHI4_SOLTU;  O24598, CHI58_ARATH;  
O24658, CHI59_ARATH;  Q9M2U5, CHI5_ARATH;  Q7Y1Z0, CHI5_ORYSJ;  
P36361, CHI5_PHAVU;  O24654, CHI60_ARATH;  O22842, CHI61_ARATH;  
O22841, CHI62_ARATH;  Q6K8R2, CHI6_ORYSJ;  P16579, CHI6_POPTR;  
Q9SAY3, CHI7_ORYSI;  Q7Y1Z1, CHI7_ORYSJ;  Q7XCK6, CHI8_ORYSJ;  
P16061, CHI8_POPTR;  Q688M5, CHI9_ORYSJ;  Q873Y0, CHIA1_ASPFM;  
Q4WEP7, CHIA1_ASPFU;  A2QUQ2, CHIA1_ASPNC;  P20533, CHIA1_BACCI;  
Q92223, CHIA1_EMEND;  G5EB30, CHIA1_EMENI;  Q06012, CHIA_ARAHY;  
P19172, CHIA_ARATH;  Q95M17, CHIA_BOVIN;  P36908, CHIA_CICAR;  
P17541, CHIA_CUCSA;  P13656, CHIA_ECOLI;  A5FB63, CHIA_FLAJ1;  
Q9BZP6, CHIA_HUMAN;  P29022, CHIA_MAIZE;  Q91XA9, CHIA_MOUSE;  
P29024, CHIA_PHAAN;  P32823, CHIA_PSEO7;  Q6RY07, CHIA_RAT;  
Q9FRV1, CHIA_SECCE;  P07254, CHIA_SERMA;  Q40114, CHIA_SOLCI;  
Q05539, CHIA_SOLLC;  P29060, CHIA_TOBAC;  Q873X9, CHIB1_ASPFM;  
E9QRF2, CHIB1_ASPFU;  G5EAZ3, CHIB1_EMENI;  Q06013, CHIB_ARAHY;  
P19171, CHIB_ARATH;  Q92222, CHIB_EMEND;  P29023, CHIB_MAIZE;  
P21227, CHIB_PEA;  P29031, CHIB_POPTR;  P11797, CHIB_SERMA;  
Q05540, CHIB_SOLLC;  P29061, CHIB_TOBAC;  P51613, CHIB_VITVI;  
P29032, CHIC_POPTR;  Q9FRV0, CHIC_SECCE;  Q05538, CHIC_SOLLC;  
P27050, CHID_BACCI;  Q05537, CHID_SOLLC;  P96156, CHID_VIBFU;  
P36910, CHIE_BETVU;  P42820, CHIP_BETVU;  P17513, CHIP_TOBAC;  
P17514, CHIQ_TOBAC;  Q13231, CHIT1_HUMAN;  Q9D7Q1, CHIT1_MOUSE;  
Q9SLP4, CHIT1_TULBA;  Q9W092, CHIT2_DROME;  Q7M443, CHIT2_TULBA;  
P51614, CHIT3_VITVI;  P86473, CHIT_ACTCH;  P86181, CHIT_AVESA;  
P29030, CHIT_BRUMA;  Q11174, CHIT_CAEEL;  P85084, CHIT_CARPA;  
P80052, CHIT_DIOJA;  P36362, CHIT_MANSE;  P41684, CHIT_NPVAC;  
O10363, CHIT_NPVOP;  P29021, CHIT_PETHY;  P06215, CHIT_PHAVU;  
P14529, CHIT_SACEN;  P05315, CHIT_SOLTU;  P36909, CHIT_STRLI;  
P11220, CHIT_STRPL;  P84754, CHIT_STRVL;  P86977, CHIT_STRVO;  
C0HJM6, CHIT_TRISX;  P29029, CHIT_YEAST;  P36907, CHIX_PEA;  
Q05638, CHIX_STROI;  O24603, CHI_ARATH;  P86955, CHI_PINMA;  
P81241, CHLY_CARPA;  P23472, CHLY_HEVBR;  P23473, CHLY_PARTH;  
P15326, IAMY_COILA;  P86799, IPLAA_MORAL;  P86800, IPLAB_MORAL;  
P09805, KTXA_KLULA;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-