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ENZYME entry: EC 22.214.171.124
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|Infectious pancreatic necrosis birnavirus Vp4 peptidase.
|Infectious pancreatic necrosis virus protease.|
|IPNV Vp4 peptidase.|
|IPNV Vp4 protease.|
|Cleaves the (Ser/Thr)-Xaa-Ala-|-(Ser/Ala)-Gly motif in the polyprotein NH(2)-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions|
- Infectious pancreatic necrosis virus (IPNV) is a birnavirus that
causes an acute, contagious disease in young salmonid fish.
- As with most viruses that infect eukaryotic cells, the proteolytic
processing of viral precursor proteins is a crucial step in the life
cycle of this virus.
- pVP2 is converted into VP2 by cleavage near the carboxy end of pVP2;
this cleavage is most likely due to host-cell proteases rather than
- Differs from most serine peptidases in not having the catalytic triad
- Belongs to peptidase family S50.
|PRIAM enzyme-specific profiles||126.96.36.199|
|KEGG Ligand Database for Enzyme Nomenclature||188.8.131.52|
|IUBMB Enzyme Nomenclature||184.108.40.206|
|MEDLINE||Find literature relating to 220.127.116.11|
entries corresponding to 3.4.21.-
entries corresponding to 3.4.-.-
entries corresponding to 3.-.-.-