ENZYME entry: EC 3.4.23.20
| Accepted Name |
|---|
| Penicillopepsin.
|
| Alternative Name(s) |
|---|
| Penicillium janthinellum aspartic protease. |
| Peptidase A. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving 20-Gly-|-Glu-21 in the B chain of insulin. Clots milk, and activates trypsinogen |
| Comment(s) |
|---|
- From the imperfect fungus Penicillium janthinellum.
- Closely related enzymes have been isolated from P.roqueforti and
P.duponti.
- Belongs to peptidase family A1.
- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.7.
|
| Cross-references |
|---|
| PROSITE | PDOC00128 |
| BRENDA | 3.4.23.20 |
| EC2PDB | 3.4.23.20 |
| ExplorEnz | 3.4.23.20 |
| PRIAM enzyme-specific profiles | 3.4.23.20 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.20 |
| IUBMB Enzyme Nomenclature | 3.4.23.20 |
| IntEnz | 3.4.23.20 |
| MEDLINE | Find literature relating to 3.4.23.20 |
| MetaCyc | 3.4.23.20 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-