ENZYME entry: EC 3.4.23.24
| Accepted Name |
|---|
| Candidapepsin.
|
| Alternative Name(s) |
|---|
| Candida albicans aspartic proteinase. |
| Reaction catalysed |
|---|
| Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 of insulin B chain. Activates trypsinogen, and degrades keratin |
| Comment(s) |
|---|
- This endopeptidase from the imperfect yeast Candida albicans is
inhibited by pepstatin, but not by methyl 2-diazoacetamido-hexanoate
or 1,2-epoxy-3-(p-nitrophenoxy)propane.
- Belongs to peptidase family A1.
- Formerly EC 3.4.4.17 and EC 3.4.23.6.
|
| Cross-references |
|---|
| PROSITE | PDOC00128 |
| BRENDA | 3.4.23.24 |
| EC2PDB | 3.4.23.24 |
| ExplorEnz | 3.4.23.24 |
| PRIAM enzyme-specific profiles | 3.4.23.24 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.24 |
| IUBMB Enzyme Nomenclature | 3.4.23.24 |
| IntEnz | 3.4.23.24 |
| MEDLINE | Find literature relating to 3.4.23.24 |
| MetaCyc | 3.4.23.24 |
| UniProtKB/Swiss-Prot |
| P0CY27, CARP1_CANAL; | C4YSF6, CARP1_CANAW; | P0CY26, CARP1_CANAX; |
| P32951, CARP1_CANPA; | P0DJ06, CARP2_CANAL; | C4YMJ3, CARP2_CANAW; |
| P0CS83, CARP2_CANAX; | P32950, CARP2_CANPA; | P0CY29, CARP3_CANAL; |
| C4YNQ5, CARP3_CANAW; | P0CY28, CARP3_CANAX; | P43093, CARP4_CANAW; |
| P43094, CARP5_CANAL; | P43095, CARP6_CANAX; | P43096, CARP7_CANAX; |
| O42778, CARP8_CANAX; | O42779, CARP9_CANAX; | Q00663, CARP_CANTR; |
|
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