Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 3.4.24.13

Accepted Name
IgA-specific metalloendopeptidase.
Alternative Name(s)
IgA protease.
Immunoglobulin A1 proteinase.
Reaction catalysed
Cleavage of Pro-|-Thr bond in the hinge region of the heavy chain of human IgA
Cofactor(s)
Zn(2+).
Comment(s)
  • Found in several pathogenic species of Streptococcus such as S.sanguis and S.pneumoniae.
  • There is also an IgA-specific prolyl endopeptidase of serine-type (see EC 3.4.21.72).
  • Belongs to peptidase family M26.
Cross-references
BRENDA3.4.24.13
EC2PDB3.4.24.13
ExplorEnz3.4.24.13
PRIAM enzyme-specific profiles3.4.24.13
KEGG Ligand Database for Enzyme Nomenclature3.4.24.13
IUBMB Enzyme Nomenclature3.4.24.13
IntEnz3.4.24.13
MEDLINEFind literature relating to 3.4.24.13
MetaCyc3.4.24.13
UniProtKB/Swiss-Prot
Q97QP7, IGA1A_STRPN;  Q54875, IGA1B_STREE;  Q59947, IGA1_STRR6;  
Q59986, IGA1_STRSA;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-