ENZYME entry: EC 3.4.24.13

Accepted Name
IgA-specific metalloendopeptidase.
Alternative Name(s)
IgA protease.
Immunoglobulin A1 proteinase.
Reaction catalysed
Cleavage of Pro-|-Thr bond in the hinge region of the heavy chain of human IgA
Cofactor(s)
Zn(2+).
Comment(s)
  • Found in several pathogenic species of Streptococcus such as S.sanguis and S.pneumoniae.
  • There is also an IgA-specific prolyl endopeptidase of serine-type (see EC 3.4.21.72).
  • Belongs to peptidase family M26.
Cross-references
BRENDA3.4.24.13
EC2PDB3.4.24.13
ExplorEnz3.4.24.13
PRIAM enzyme-specific profiles3.4.24.13
KEGG Ligand Database for Enzyme Nomenclature3.4.24.13
IUBMB Enzyme Nomenclature3.4.24.13
IntEnz3.4.24.13
MEDLINEFind literature relating to 3.4.24.13
MetaCyc3.4.24.13
UniProtKB/Swiss-Prot
Q97QP7, IGA1A_STRPN;  Q54875, IGA1B_STREE;  Q59947, IGA1_STRR6;  
Q59986, IGA1_STRSA;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-