ENZYME entry: EC 3.5.1.77

Accepted Name
N-carbamoyl-D-amino-acid hydrolase.
Alternative Name(s)
D-N-carbamoylase.
N-carbamoyl-D-amino acid hydrolase.
N-carbamoylase.
Reaction catalysed
N-carbamoyl-D-amino acid + H(2)O <=> D-amino acid + NH(3) + CO(2)
Comment(s)
  • This enzyme, along with EC 3.5.1.87, EC 5.1.99.5 and EC 3.5.2.2, forms part of the reaction cascade known as the 'hydantoinase process', which allows the total conversion of D,L-5-monosubstituted hydantoins into optically pure D- or L-amino acids.
  • Has strict stereospecificity for N-carbamoyl-D-amino acids and does not act upon the corresponding L-amino acids or N-formyl amino acids, N-carbamoyl-sarcosine, -citrulline, -allantoin and -ureidopropanoate, which are substrates for other amidohydrolases.
Cross-references
BRENDA3.5.1.77
EC2PDB3.5.1.77
ExplorEnz3.5.1.77
PRIAM enzyme-specific profiles3.5.1.77
KEGG Ligand Database for Enzyme Nomenclature3.5.1.77
IUBMB Enzyme Nomenclature3.5.1.77
IntEnz3.5.1.77
MEDLINEFind literature relating to 3.5.1.77
MetaCyc3.5.1.77
UniProtKB/Swiss-Prot
P60327, DCAS_AGRSK;  Q5S260, DCAS_ENSAD;  Q44185, DCAS_RHIRD;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
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