ENZYME entry: EC 3.5.4.16

Accepted Name
GTP cyclohydrolase I.
Reaction catalysed
GTP + H(2)O <=> formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate
Comment(s)
  • The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic.
  • Involved in the de novo synthesis of tetrahydrobiopterin from GTP, with the other enzymes involved being EC 1.1.1.153 and EC 4.2.3.12.
Cross-references
PROSITEPDOC00672
BRENDA3.5.4.16
EC2PDB3.5.4.16
ExplorEnz3.5.4.16
PRIAM enzyme-specific profiles3.5.4.16
KEGG Ligand Database for Enzyme Nomenclature3.5.4.16
IUBMB Enzyme Nomenclature3.5.4.16
IntEnz3.5.4.16
MEDLINEFind literature relating to 3.5.4.16
MetaCyc3.5.4.16
UniProtKB/Swiss-Prot
Q9CGE3, FOLKE_LACLA;  Q8GJP4, FOLKE_LACLM;  Q8YLL1, GCH11_NOSS1;  
Q9HYG8, GCH11_PSEAE;  Q88LV4, GCH11_PSEPK;  Q887V1, GCH11_PSESM;  
Q8YN49, GCH12_NOSS1;  Q9I351, GCH12_PSEAE;  Q88JY1, GCH12_PSEPK;  
Q884Q3, GCH12_PSESM;  A3N0R3, GCH1_ACTP2;  B3GXP9, GCH1_ACTP7;  
B0BPI8, GCH1_ACTPJ;  A0KIN6, GCH1_AERHH;  A4SPE8, GCH1_AERS4;  
Q8UEK8, GCH1_AGRT5;  B9JWF1, GCH1_AGRVS;  B6EGN8, GCH1_ALISL;  
Q0A939, GCH1_ALKEH;  O66603, GCH1_AQUAE;  Q9SFV7, GCH1_ARATH;  
A8HUG2, GCH1_AZOC5;  C1DHG2, GCH1_AZOVD;  A7Z630, GCH1_BACA2;  
C3P598, GCH1_BACAA;  C3L8S8, GCH1_BACAC;  A0RBW5, GCH1_BACAH;  
Q81SW2, GCH1_BACAN;  B7JGZ6, GCH1_BACC0;  Q73AY4, GCH1_BACC1;  
B7IP89, GCH1_BACC2;  C1EN08, GCH1_BACC3;  B7HHR5, GCH1_BACC4;  
B7HL21, GCH1_BACC7;  A7GN48, GCH1_BACCN;  B9IVN3, GCH1_BACCQ;  
Q81FQ8, GCH1_BACCR;  Q63DM1, GCH1_BACCZ;  Q5L925, GCH1_BACFN;  
Q64P85, GCH1_BACFR;  Q9KCC7, GCH1_BACHD;  Q6HL44, GCH1_BACHK;  
A8FEL2, GCH1_BACP2;  P48063, GCH1_BACPU;  P19465, GCH1_BACSU;  
Q8A0U0, GCH1_BACTN;  A9VMC0, GCH1_BACWK;  A1USJ5, GCH1_BARBK;  
Q6G3J8, GCH1_BARHE;  Q6FZZ4, GCH1_BARQU;  Q1LT77, GCH1_BAUCH;  
B2IBC4, GCH1_BEII9;  B3DR12, GCH1_BIFLD;  Q8G3S1, GCH1_BIFLO;  
Q7VRX3, GCH1_BLOFL;  Q492J7, GCH1_BLOPB;  Q89IW2, GCH1_BRADU;  
C0ZCC7, GCH1_BREBN;  B2S5T0, GCH1_BRUA1;  Q2YQ03, GCH1_BRUA2;  
Q57D61, GCH1_BRUAB;  A9M586, GCH1_BRUC2;  C0RJ47, GCH1_BRUMB;  
Q8YH94, GCH1_BRUME;  A5VQL0, GCH1_BRUO2;  B0CGM4, GCH1_BRUSI;  
Q8G0L4, GCH1_BRUSU;  Q8KA05, GCH1_BUCAP;  Q19980, GCH1_CAEEL;  
A8MC60, GCH1_CALMQ;  Q8R7N2, GCH1_CALS4;  A7ZB36, GCH1_CAMC1;  
A7GW42, GCH1_CAMC5;  A8FJZ5, GCH1_CAMJ8;  A7H1R1, GCH1_CAMJD;  
P51594, GCH1_CAMJE;  A1VXS2, GCH1_CAMJJ;  Q5HWX4, GCH1_CAMJR;  
B9KDZ8, GCH1_CAMLR;  Q3ADI2, GCH1_CARHZ;  Q9AAY3, GCH1_CAUCR;  
Q11JM4, GCH1_CHESB;  P50141, GCH1_CHICK;  Q3ATN0, GCH1_CHLCH;  
Q8KEA8, GCH1_CHLTE;  Q1QV64, GCH1_CHRSD;  Q7NYZ2, GCH1_CHRVO;  
A8AE79, GCH1_CITK8;  Q97D54, GCH1_CLOAB;  A7FU67, GCH1_CLOB1;  
C3KVW3, GCH1_CLOB6;  A6LWG6, GCH1_CLOB8;  A5I231, GCH1_CLOBH;  
C1FN26, GCH1_CLOBJ;  B1IL94, GCH1_CLOBK;  A7GDP1, GCH1_CLOBL;  
B1L1S1, GCH1_CLOBM;  B8I184, GCH1_CLOCE;  B9E092, GCH1_CLOK1;  
A5N6S3, GCH1_CLOK5;  A0Q2L7, GCH1_CLONN;  Q0TRM0, GCH1_CLOP1;  
Q8XLM2, GCH1_CLOPE;  Q0STY9, GCH1_CLOPS;  A3DHH6, GCH1_CLOTH;  
C3PJE8, GCH1_CORA7;  Q8FMG3, GCH1_COREF;  A4QH94, GCH1_CORGB;  
Q8NM84, GCH1_CORGL;  A9KFF3, GCH1_COXBN;  A9NDB3, GCH1_COXBR;  
Q83DE3, GCH1_COXBU;  Q3Z782, GCH1_DEHM1;  A5FQD3, GCH1_DEHMB;  
Q3ZYB5, GCH1_DEHMC;  Q9RYB4, GCH1_DEIRA;  A4J5D0, GCH1_DESRM;  
Q94465, GCH1_DICDI;  P48596, GCH1_DROME;  A7ZNX6, GCH1_ECO24;  
B7UFG9, GCH1_ECO27;  B7MF66, GCH1_ECO45;  B7LAH4, GCH1_ECO55;  
P0A6T7, GCH1_ECO57;  B5YWU3, GCH1_ECO5E;  B7NMB8, GCH1_ECO7I;  
B7MXG6, GCH1_ECO81;  B7M4Z9, GCH1_ECO8A;  C4ZU03, GCH1_ECOBW;  
B1X7P1, GCH1_ECODH;  A8A214, GCH1_ECOHS;  A1AD13, GCH1_ECOK1;  
Q0TFT7, GCH1_ECOL5;  P0A6T6, GCH1_ECOL6;  B1IYB6, GCH1_ECOLC;  
P0A6T5, GCH1_ECOLI;  B7NCI3, GCH1_ECOLU;  B6I8K3, GCH1_ECOSE;  
B1LKQ0, GCH1_ECOSM;  Q1R9R9, GCH1_ECOUT;  C5BCL9, GCH1_EDWI9;  
A4WCI8, GCH1_ENT38;  Q82Z12, GCH1_ENTFA;  B2VII2, GCH1_ERWT9;  
B7LVB3, GCH1_ESCF3;  P51597, GCH1_EUGGR;  B0S1R1, GCH1_FINM2;  
A5FHM7, GCH1_FLAJ1;  Q8RH43, GCH1_FUSNN;  Q5KXT7, GCH1_GEOKA;  
C5D3E8, GCH1_GEOSW;  Q7NK98, GCH1_GLOVI;  Q7VM90, GCH1_HAEDU;  
Q4QKH4, GCH1_HAEI8;  A5UC59, GCH1_HAEIE;  A5UEW4, GCH1_HAEIG;  
P43866, GCH1_HAEIN;  Q2SPJ2, GCH1_HAHCH;  C4K3L4, GCH1_HAMD5;  
Q17WX5, GCH1_HELAH;  Q7VFG4, GCH1_HELHP;  B6JME9, GCH1_HELP2;  
B5Z7T2, GCH1_HELPG;  Q1CSU6, GCH1_HELPH;  Q9ZKS2, GCH1_HELPJ;  
B2UU76, GCH1_HELPS;  P56462, GCH1_HELPY;  Q0I3F6, GCH1_HISS1;  
B0UUA9, GCH1_HISS2;  P30793, GCH1_HUMAN;  B4U640, GCH1_HYDS0;  
A2BL58, GCH1_HYPBU;  Q0BXB5, GCH1_HYPNA;  A6SZ52, GCH1_JANMA;  
B5XP57, GCH1_KLEP3;  A6TBN8, GCH1_KLEP7;  Q88ST4, GCH1_LACPL;  
Q38WN0, GCH1_LACSS;  Q6ACQ1, GCH1_LEIXX;  B0S8X8, GCH1_LEPBA;  
Q04P36, GCH1_LEPBJ;  Q056J8, GCH1_LEPBL;  B0SRX6, GCH1_LEPBP;  
Q72LY8, GCH1_LEPIC;  Q8EYG1, GCH1_LEPIN;  Q92A75, GCH1_LISIN;  
C1KWN3, GCH1_LISMC;  Q71Y82, GCH1_LISMF;  B8DBZ3, GCH1_LISMH;  
Q8Y5X1, GCH1_LISMO;  A0AK45, GCH1_LISW6;  B1HTA3, GCH1_LYSSC;  
Q65TR0, GCH1_MANSM;  Q0AM02, GCH1_MARMM;  Q607T5, GCH1_METCA;  
B0U881, GCH1_METS4;  Q05915, GCH1_MOUSE;  P51598, GCH1_MUCPU;  
A0QA85, GCH1_MYCA1;  B1MGU9, GCH1_MYCA9;  P64208, GCH1_MYCBO;  
A1KPU4, GCH1_MYCBP;  C1AI67, GCH1_MYCBT;  A4T5P2, GCH1_MYCGI;  
B8ZU42, GCH1_MYCLB;  O69531, GCH1_MYCLE;  B2HJ53, GCH1_MYCMM;  
Q743Z2, GCH1_MYCPA;  A5U8T4, GCH1_MYCTA;  P9WN56, GCH1_MYCTO;  
P9WN57, GCH1_MYCTU;  A0PV57, GCH1_MYCUA;  A1TG42, GCH1_MYCVP;  
P51599, GCH1_NEUCR;  Q2Y6B3, GCH1_NITMU;  B2J1L7, GCH1_NOSP7;  
A6X0X0, GCH1_OCHA4;  P51596, GCH1_ONCMY;  O61573, GCH1_OSTOS;  
A6LFE8, GCH1_PARD8;  P57865, GCH1_PASMU;  Q6D3N3, GCH1_PECAS;  
C6DEM6, GCH1_PECCP;  A5D2D8, GCH1_PELTS;  Q4FL89, GCH1_PELUB;  
Q18BW7, GCH1_PEPD6;  C0QPU5, GCH1_PERMH;  Q7N6K7, GCH1_PHOLL;  
Q6LQL4, GCH1_PHOPR;  P51600, GCH1_PHYBL;  B2RIJ1, GCH1_PORG3;  
Q7MWI5, GCH1_PORGI;  A4SF37, GCH1_PROVI;  Q15YG1, GCH1_PSEA6;  
Q3IF89, GCH1_PSEHT;  Q8ZWW5, GCH1_PYRAE;  B1YCT7, GCH1_PYRNV;  
Q8XZK8, GCH1_RALSO;  P22288, GCH1_RAT;  Q98LQ6, GCH1_RHILO;  
Q92QB4, GCH1_RHIME;  C3MB45, GCH1_RHISN;  Q7UJJ7, GCH1_RHOBA;  
Q2IY20, GCH1_RHOP2;  Q6N4E7, GCH1_RHOPA;  Q212N0, GCH1_RHOPB;  
Q134L7, GCH1_RHOPS;  B3QE25, GCH1_RHOPT;  C3PNA0, GCH1_RICAE;  
A8GN89, GCH1_RICAH;  A8GUB6, GCH1_RICB8;  Q1RID0, GCH1_RICBR;  
Q92I93, GCH1_RICCN;  Q4ULX3, GCH1_RICFE;  A8F1F2, GCH1_RICM5;  
Q9ZDE8, GCH1_RICPR;  C4K2D8, GCH1_RICPU;  B0BXB8, GCH1_RICRO;  
A8GRW0, GCH1_RICRS;  Q68WZ4, GCH1_RICTY;  B5EYP3, GCH1_SALA4;  
A9MK63, GCH1_SALAR;  Q57ME6, GCH1_SALCH;  B5FNJ7, GCH1_SALDC;  
B5R163, GCH1_SALEP;  B5RC32, GCH1_SALG2;  B4TAL5, GCH1_SALHS;  
B4SY26, GCH1_SALNS;  Q5PE52, GCH1_SALPA;  A9N6K0, GCH1_SALPB;  
C0Q0U7, GCH1_SALPC;  B5BE43, GCH1_SALPK;  B4TNQ0, GCH1_SALSV;  
P64210, GCH1_SALTI;  P64209, GCH1_SALTY;  O13774, GCH1_SCHPO;  
A8GC24, GCH1_SERP5;  A1S2C7, GCH1_SHEAM;  B8E4J0, GCH1_SHEB2;  
A3CZJ1, GCH1_SHEB5;  A6WIA1, GCH1_SHEB8;  A9KXZ9, GCH1_SHEB9;  
Q12SG0, GCH1_SHEDO;  A3QIQ4, GCH1_SHELP;  Q8E9L6, GCH1_SHEON;  
A4Y2K7, GCH1_SHEPC;  A0L1S4, GCH1_SHESA;  Q0HE51, GCH1_SHESM;  
Q0HZU8, GCH1_SHESR;  A1REU0, GCH1_SHESW;  B2TVT9, GCH1_SHIB3;  
Q31YW1, GCH1_SHIBS;  Q32EN8, GCH1_SHIDS;  Q0T2X1, GCH1_SHIF8;  
P0A6T8, GCH1_SHIFL;  Q3Z053, GCH1_SHISS;  A6U8C2, GCH1_SINMW;  
Q2NUE3, GCH1_SODGM;  Q8VYU3, GCH1_SOLLC;  Q3K0Y1, GCH1_STRA1;  
Q8E549, GCH1_STRA3;  Q8DZI5, GCH1_STRA5;  Q82EE8, GCH1_STRAW;  
Q9X8I3, GCH1_STRCO;  A8AZD8, GCH1_STRGC;  B1VSG4, GCH1_STRGG;  
Q8DUG2, GCH1_STRMU;  P0C0C2, GCH1_STRP1;  Q04MF9, GCH1_STRP2;  
P0DB30, GCH1_STRP3;  B5E6W5, GCH1_STRP4;  Q5XCA9, GCH1_STRP6;  
C1CB65, GCH1_STRP7;  P0A3E9, GCH1_STRP8;  A2REL9, GCH1_STRPG;  
B1I918, GCH1_STRPI;  B8ZL26, GCH1_STRPJ;  P51595, GCH1_STRPN;  
P0DB31, GCH1_STRPQ;  B2ISL9, GCH1_STRPS;  P0C0C1, GCH1_STRPY;  
B5XLE8, GCH1_STRPZ;  P59656, GCH1_STRR6;  A4W1S9, GCH1_STRS2;  
A3CKF4, GCH1_STRSV;  A4VVH1, GCH1_STRSY;  Q5LYM8, GCH1_STRT1;  
Q5M391, GCH1_STRT2;  C1CC81, GCH1_STRZJ;  C1CIH2, GCH1_STRZP;  
C1CPG4, GCH1_STRZT;  Q4J8S2, GCH1_SULAC;  C3MZ97, GCH1_SULIA;  
C4KIH5, GCH1_SULIK;  C3MR62, GCH1_SULIL;  C3MXF1, GCH1_SULIM;  
C3NGB7, GCH1_SULIN;  C3N7B7, GCH1_SULIY;  Q980E8, GCH1_SULSO;  
B2V9P4, GCH1_SULSY;  Q971G9, GCH1_SULTO;  Q54769, GCH1_SYNE7;  
Q2JR69, GCH1_SYNJA;  Q2JPT8, GCH1_SYNJB;  Q5N623, GCH1_SYNP6;  
Q55759, GCH1_SYNY3;  C5BL73, GCH1_TERTT;  Q8DJB8, GCH1_THEEB;  
Q47KU5, GCH1_THEFY;  B0KCE5, GCH1_THEP3;  B0K5C1, GCH1_THEPX;  
B5YJV0, GCH1_THEYD;  C4LDE6, GCH1_TOLAT;  A7N6L2, GCH1_VIBCB;  
Q9KLX5, GCH1_VIBCH;  Q5E4E4, GCH1_VIBF1;  B5FF36, GCH1_VIBFM;  
Q87GZ6, GCH1_VIBPA;  Q8D6I7, GCH1_VIBVU;  Q7MDE5, GCH1_VIBVY;  
Q8D2N7, GCH1_WIGBR;  Q7M933, GCH1_WOLSU;  Q8PEP3, GCH1_XANAC;  
Q3BM80, GCH1_XANC5;  Q8P3B0, GCH1_XANCP;  B2I4L2, GCH1_XYLF2;  
Q9PC02, GCH1_XYLFA;  B0U794, GCH1_XYLFM;  Q87D63, GCH1_XYLFT;  
P51601, GCH1_YEAST;  A1JU09, GCH1_YERE8;  A7FJL1, GCH1_YERP3;  
B2JZ02, GCH1_YERPB;  Q8ZG15, GCH1_YERPE;  A9R1B1, GCH1_YERPG;  
B1JQJ4, GCH1_YERPY;  Q1BR24, GCH41_BURCA;  B1K3S8, GCH41_BURCC;  
A0AYZ1, GCH41_BURCH;  Q39AS8, GCH41_BURS3;  Q47IT5, GCH41_DECAR;  
Q1LPE1, GCH41_RALME;  Q1BLY8, GCH42_BURCA;  B1K5N3, GCH42_BURCC;  
A0B338, GCH42_BURCH;  Q393P5, GCH42_BURS3;  Q47BI9, GCH42_DECAR;  
Q1LK35, GCH42_RALME;  Q6FBI2, GCH4_ACIAD;  B2ULP4, GCH4_AKKM8;  
Q0VMK6, GCH4_ALCBS;  Q0AA39, GCH4_ALKEH;  Q5P229, GCH4_AROAE;  
A1K4Q9, GCH4_AZOSB;  C1DM03, GCH4_AZOVD;  Q9KE60, GCH4_BACHD;  
Q65ML7, GCH4_BACLD;  P94398, GCH4_BACSU;  Q6MKE9, GCH4_BDEBA;  
Q2KZ16, GCH4_BORA1;  Q7WL36, GCH4_BORBR;  Q7W7P9, GCH4_BORPA;  
A9ITA7, GCH4_BORPD;  Q7VV88, GCH4_BORPE;  B1Z1G3, GCH4_BURA4;  
Q0BAL7, GCH4_BURCM;  A9ANA1, GCH4_BURM1;  A3MBD3, GCH4_BURM7;  
A2S0N7, GCH4_BURM9;  Q62DU0, GCH4_BURMA;  A1UYQ5, GCH4_BURMS;  
A3P7W3, GCH4_BURP0;  Q3JKA4, GCH4_BURP1;  A3NMF5, GCH4_BURP6;  
B2JP67, GCH4_BURP8;  Q63JF5, GCH4_BURPS;  Q2T7N4, GCH4_BURTA;  
A4JLT5, GCH4_BURVG;  Q13RX0, GCH4_BURXL;  B9MNP4, GCH4_CALBD;  
A4XG24, GCH4_CALS8;  Q1R153, GCH4_CHRSD;  A8AF20, GCH4_CITK8;  
Q47VM6, GCH4_COLP3;  B5Y6R9, GCH4_COPPD;  Q0K861, GCH4_CUPNH;  
Q474C1, GCH4_CUPPJ;  A9C020, GCH4_DELAS;  C6C0U6, GCH4_DESAD;  
Q30X45, GCH4_DESAG;  B8J1Q5, GCH4_DESDA;  A8ZUJ6, GCH4_DESOH;  
Q6AMT5, GCH4_DESPS;  Q727G3, GCH4_DESVH;  B8DLK8, GCH4_DESVM;  
A1VAN0, GCH4_DESVV;  A5EXB0, GCH4_DICNV;  B5YCT4, GCH4_DICT6;  
B8DZH0, GCH4_DICTD;  A8LS52, GCH4_DINSH;  B1YHT1, GCH4_EXIS2;  
C4KZ55, GCH4_EXISA;  A7HKP2, GCH4_FERNB;  B5EDQ6, GCH4_GEOBB;  
Q39R36, GCH4_GEOMG;  Q74FW8, GCH4_GEOSL;  C6E7E6, GCH4_GEOSM;  
A5G8S1, GCH4_GEOUR;  Q2SLC0, GCH4_HAHCH;  A1WYI8, GCH4_HALHL;  
A4G1X0, GCH4_HERAR;  Q5R041, GCH4_IDILO;  A6SUS5, GCH4_JANMA;  
Q28R88, GCH4_JANSC;  Q6U5S4, GCH4_KLEPN;  C5CEC0, GCH4_KOSOT;  
Q1MPD2, GCH4_LAWIP;  B9E8N6, GCH4_MACCJ;  A0L8I1, GCH4_MAGSM;  
Q605G6, GCH4_METCA;  Q1GZD6, GCH4_METFK;  A2SJ45, GCH4_METPP;  
Q5F9K6, GCH4_NEIG1;  A9M3N5, GCH4_NEIM0;  Q9JV35, GCH4_NEIMA;  
Q9K023, GCH4_NEIMB;  A1KT61, GCH4_NEIMF;  Q0AFY5, GCH4_NITEC;  
Q82VD1, GCH4_NITEU;  Q2YCH6, GCH4_NITMU;  Q3J9J7, GCH4_NITOC;  
Q8EQK9, GCH4_OCEIH;  B1ZTR5, GCH4_OPITP;  A1BA17, GCH4_PARDP;  
Q3A091, GCH4_PELCD;  A1AU47, GCH4_PELPD;  A4SZK2, GCH4_POLSQ;  
Q48HN1, GCH4_PSE14;  Q15Z55, GCH4_PSEA6;  A6VF17, GCH4_PSEA7;  
B7V776, GCH4_PSEA8;  Q02DG9, GCH4_PSEAB;  Q9HT35, GCH4_PSEAE;  
Q1I2L2, GCH4_PSEE4;  Q4K3E8, GCH4_PSEF5;  C3K4H5, GCH4_PSEFS;  
Q3ILJ5, GCH4_PSEHT;  A4Y119, GCH4_PSEMY;  A5W348, GCH4_PSEP1;  
Q3K4B0, GCH4_PSEPF;  B0KR89, GCH4_PSEPG;  Q88HM9, GCH4_PSEPK;  
B1JFN3, GCH4_PSEPW;  Q882P7, GCH4_PSESM;  Q4ZU60, GCH4_PSEU2;  
A1STF0, GCH4_PSYIN;  Q8XX96, GCH4_RALSO;  A3PH01, GCH4_RHOS1;  
Q3J5D3, GCH4_RHOS4;  A4WQ81, GCH4_RHOS5;  B9KM22, GCH4_RHOSK;  
Q168P4, GCH4_ROSDO;  Q5LTR1, GCH4_RUEPO;  Q1GF96, GCH4_RUEST;  
A1AVX5, GCH4_RUTMC;  A8GF39, GCH4_SERP5;  A7WZ02, GCH4_STAA1;  
A6TZ43, GCH4_STAA2;  Q2FJ74, GCH4_STAA3;  Q2G0L1, GCH4_STAA8;  
A5IQC0, GCH4_STAA9;  Q2YS98, GCH4_STAAB;  Q5HIA9, GCH4_STAAC;  
A6QEL9, GCH4_STAAE;  Q99W43, GCH4_STAAM;  Q7A777, GCH4_STAAN;  
Q6GJA3, GCH4_STAAR;  Q6GBS1, GCH4_STAAS;  A8YZR4, GCH4_STAAT;  
Q8NXX2, GCH4_STAAW;  B9DKT0, GCH4_STACT;  Q5HRI1, GCH4_STAEQ;  
Q8CTR6, GCH4_STAES;  Q4L3P5, GCH4_STAHJ;  Q49VB3, GCH4_STAS1;  
Q2LUP0, GCH4_SYNAS;  A0LQR3, GCH4_SYNFM;  B7ICT4, GCH4_THEAB;  
A8F7Q8, GCH4_THELT;  A6LKE7, GCH4_THEM4;  Q9WXP6, GCH4_THEMA;  
B9K795, GCH4_THENN;  A5IL29, GCH4_THEP1;  B1LAA9, GCH4_THESQ;  
Q31EF8, GCH4_THICR;  Q3SKF2, GCH4_THIDA;  A5CXA1, GCH4_VESOH;  
Q8PLL4, GCH4_XANAC;  Q3BUL9, GCH4_XANC5;  Q4UTV2, GCH4_XANC8;  
B0RTU4, GCH4_XANCB;  Q8P9T3, GCH4_XANCP;  Q2P374, GCH4_XANOM;  
B2SJL4, GCH4_XANOP;  Q5H0A0, GCH4_XANOR;  B2IAI3, GCH4_XYLF2;  
Q9PBP4, GCH4_XYLFA;  B0U741, GCH4_XYLFM;  Q87DA5, GCH4_XYLFT;  
P45371, GTPC1_ALLVD;  O28497, GTPC1_ARCFU;  Q9KD39, GTPC1_BACHD;  
P54472, GTPC1_BACSU;  O51424, GTPC1_BORBU;  Q05B89, GTPC1_BOVIN;  
P57387, GTPC1_BUCAI;  Q8K9N4, GTPC1_BUCAP;  Q89AJ8, GTPC1_BUCBP;  
Q9PPK2, GTPC1_CAMJE;  Q9PKS8, GTPC1_CHLMU;  Q9Z946, GTPC1_CHLPN;  
O84110, GTPC1_CHLTR;  Q97JI0, GTPC1_CLOAB;  Q8XIV9, GTPC1_CLOPE;  
Q9RY41, GTPC1_DEIRA;  Q55E83, GTPC1_DICDI;  Q9NK57, GTPC1_DROME;  
P0AFP8, GTPC1_ECO57;  P0AFP7, GTPC1_ECOL6;  P0AFP6, GTPC1_ECOLI;  
Q57354, GTPC1_HAEIN;  Q9HP80, GTPC1_HALSA;  Q9ZKP2, GTPC1_HELPJ;  
O25613, GTPC1_HELPY;  Q9GZT8, GTPC1_HUMAN;  Q9CGM3, GTPC1_LACLA;  
Q92BQ8, GTPC1_LISIN;  P53434, GTPC1_LISMO;  Q58337, GTPC1_METJA;  
O27214, GTPC1_METTH;  Q9EQ80, GTPC1_MOUSE;  P0A657, GTPC1_MYCBO;  
O69481, GTPC1_MYCLE;  Q98QB0, GTPC1_MYCPU;  P9WFM0, GTPC1_MYCTO;  
P9WFM1, GTPC1_MYCTU;  Q9JWG6, GTPC1_NEIMA;  Q9JXG9, GTPC1_NEIMB;  
Q8YS75, GTPC1_NOSS1;  Q9CP72, GTPC1_PASMU;  Q9HVX2, GTPC1_PSEAE;  
Q9UYT3, GTPC1_PYRAB;  O58361, GTPC1_PYRHO;  Q8XVA0, GTPC1_RALSO;  
Q4V7D6, GTPC1_RAT;  P67271, GTPC1_SALTI;  P67270, GTPC1_SALTY;  
O94404, GTPC1_SCHPO;  Q5HFK1, GTPC1_STAAC;  P67272, GTPC1_STAAM;  
P67273, GTPC1_STAAN;  Q6GGE0, GTPC1_STAAR;  Q6G907, GTPC1_STAAS;  
Q8NWB9, GTPC1_STAAW;  Q5HNY9, GTPC1_STAEQ;  Q8CSD9, GTPC1_STAES;  
Q9L012, GTPC1_STRCO;  P67274, GTPC1_STRP1;  P0DG84, GTPC1_STRP3;  
Q5XCH0, GTPC1_STRP6;  P67276, GTPC1_STRP8;  Q97PK0, GTPC1_STRPN;  
P0DG85, GTPC1_STRPQ;  O83942, GTPC1_TREPA;  Q9PQE0, GTPC1_UREPA;  
Q9KQA7, GTPC1_VIBCH;  P53081, GTPC1_YEAST;  Q8ZD91, GTPC1_YERPE;  

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