ENZYME entry: EC 3.6.1.1

Accepted Name
Inorganic diphosphatase.
Alternative Name(s)
Diphosphate phosphohydrolase.
Inorganic pyrophosphatase.
Pyrophosphate phosphohydrolase.
Reaction catalysed
Diphosphate + H(2)O <=> 2 phosphate
Comment(s)
  • Specificity varies with the source and with the activating metal ion.
  • The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9.
Cross-references
PROSITEPDOC00325
BRENDA3.6.1.1
EC2PDB3.6.1.1
ExplorEnz3.6.1.1
PRIAM enzyme-specific profiles3.6.1.1
KEGG Ligand Database for Enzyme Nomenclature3.6.1.1
IUBMB Enzyme Nomenclature3.6.1.1
IntEnz3.6.1.1
MEDLINEFind literature relating to 3.6.1.1
MetaCyc3.6.1.1
UniProtKB/Swiss-Prot
P31414, AVP1_ARATH;  Q56ZN6, AVP2_ARATH;  Q9FWR2, AVPX_ARATH;  
Q06572, AVP_HORVU;  P21616, AVP_VIGRR;  Q8TJA9, HPPA1_METAC;  
Q8PYZ8, HPPA1_METMA;  Q2RIS7, HPPA1_MOOTA;  Q93AR8, HPPA1_MYCDI;  
Q93AS0, HPPA1_RHILT;  Q8TJA8, HPPA2_METAC;  Q8PYZ7, HPPA2_METMA;  
Q2RLE0, HPPA2_MOOTA;  Q93AR9, HPPA2_MYCDI;  Q93AS1, HPPA2_RHILT;  
Q8UG67, HPPA_AGRFC;  Q8VNU8, HPPA_ALLVI;  Q8VRZ1, HPPA_ANAMA;  
Q8A294, HPPA_BACTN;  Q89K83, HPPA_BRADU;  Q8YGH4, HPPA_BRUME;  
Q8G1E6, HPPA_BRUSU;  Q8RCX1, HPPA_CALS4;  Q3AFC6, HPPA_CARHZ;  
Q9A8J0, HPPA_CAUCR;  Q8VNW3, HPPA_CHLAA;  Q8KDT8, HPPA_CHLTE;  
Q898Q9, HPPA_CLOTE;  Q8RHJ2, HPPA_FUSNN;  Q8VNJ8, HPPA_HELCL;  
Q72Q29, HPPA_LEPIC;  Q8F641, HPPA_LEPIN;  Q93NB7, HPPA_MYXXA;  
Q82TF3, HPPA_NITEU;  Q8VRZ2, HPPA_OCHA4;  Q8ZWI8, HPPA_PYRAE;  
Q983A3, HPPA_RHILO;  Q8VRZ3, HPPA_RHIME;  Q8VPZ0, HPPA_RHIRD;  
P60363, HPPA_RHOPA;  Q8KY01, HPPA_RHOPL;  O68460, HPPA_RHORT;  
Q82EJ8, HPPA_STRAW;  Q9X913, HPPA_STRCO;  Q9S5X0, HPPA_THEMA;  
Q8PH20, HPPA_XANAC;  Q8P5M6, HPPA_XANCP;  Q93V56, IPYR1_ARATH;  
Q93Y52, IPYR1_CHLRE;  Q889M7, IPYR1_PSESM;  P21216, IPYR2_ARATH;  
Q949J1, IPYR2_CHLRE;  Q9H2U2, IPYR2_HUMAN;  Q91VM9, IPYR2_MOUSE;  
Q87WD6, IPYR2_PSESM;  P87118, IPYR2_SCHPO;  P28239, IPYR2_YEAST;  
O82793, IPYR3_ARATH;  Q9LFF9, IPYR4_ARATH;  O82597, IPYR5_ARATH;  
Q9LXC9, IPYR6_ARATH;  Q9YBA5, IPYR_AERPE;  Q8UC37, IPYR_AGRFC;  
O67501, IPYR_AQUAE;  Q8GQS5, IPYR_AQUPY;  Q757J8, IPYR_ASHGO;  
Q9KCG7, IPYR_BACHD;  P19514, IPYR_BACP3;  P51064, IPYR_BARBK;  
P82992, IPYR_BLAVI;  P37980, IPYR_BOVIN;  Q89WY0, IPYR_BRADU;  
P65744, IPYR_BRUME;  P65745, IPYR_BRUSU;  P57190, IPYR_BUCAI;  
Q8KA31, IPYR_BUCAP;  P59417, IPYR_BUCBP;  Q18680, IPYR_CAEEL;  
Q9PHM9, IPYR_CAMJE;  P83777, IPYR_CANAL;  Q6FRB7, IPYR_CANGA;  
Q9AC20, IPYR_CAUCR;  Q821T4, IPYR_CHLCV;  Q9PLF1, IPYR_CHLMU;  
Q9Z6Y8, IPYR_CHLPN;  B0B8Z8, IPYR_CHLT2;  Q3KKS0, IPYR_CHLTA;  
B0BAM7, IPYR_CHLTB;  O84777, IPYR_CHLTR;  Q8XIQ9, IPYR_CLOPE;  
Q8FMF8, IPYR_COREF;  Q8NM79, IPYR_CORGL;  P80887, IPYR_CYAPA;  
Q6BWA5, IPYR_DEBHA;  P19371, IPYR_DESVH;  Q54PV8, IPYR_DICDI;  
O77460, IPYR_DROME;  P0A7B0, IPYR_ECO57;  Q8FAG0, IPYR_ECOL6;  
P0A7A9, IPYR_ECOLI;  Q5B912, IPYR_EMENI;  Q8SR69, IPYR_ENCCU;  
P81987, IPYR_EUGGR;  O05724, IPYR_GEOSE;  O05545, IPYR_GLUOX;  
Q7VPC0, IPYR_HAEDU;  P44529, IPYR_HAEIN;  Q9HSF3, IPYR_HALSA;  
Q9ZLL5, IPYR_HELPJ;  P56153, IPYR_HELPY;  O23979, IPYR_HORVD;  
Q15181, IPYR_HUMAN;  P13998, IPYR_KLULA;  O34955, IPYR_LEGPN;  
Q6ACP7, IPYR_LEIXX;  Q72MG4, IPYR_LEPIC;  Q8EZ21, IPYR_LEPIN;  
Q4R543, IPYR_MACFA;  O48556, IPYR_MAIZE;  Q8TMI3, IPYR_METAC;  
Q8TVE2, IPYR_METKA;  Q8PWY5, IPYR_METMA;  O26363, IPYR_METTH;  
Q9D819, IPYR_MOUSE;  P65747, IPYR_MYCBO;  P47593, IPYR_MYCGE;  
O69540, IPYR_MYCLE;  Q8EVW9, IPYR_MYCPE;  P75250, IPYR_MYCPN;  
Q98Q96, IPYR_MYCPU;  P9WI54, IPYR_MYCTO;  P9WI55, IPYR_MYCTU;  
Q74MY6, IPYR_NANEQ;  Q9JVG3, IPYR_NEIMA;  Q9K0G4, IPYR_NEIMB;  
Q6MVH7, IPYR_NEUCR;  P80562, IPYR_NOSS1;  P81988, IPYR_OCHDN;  
A2X8Q3, IPYR_ORYSI;  Q0DYB1, IPYR_ORYSJ;  P57918, IPYR_PASMU;  
O13505, IPYR_PICPA;  Q6KZB3, IPYR_PICTO;  O77392, IPYR_PLAF7;  
Q5R8T6, IPYR_PONAB;  Q9HWZ6, IPYR_PSEAE;  P58733, IPYR_PSEAO;  
P0CAP8, IPYR_PSEGP;  Q88QF6, IPYR_PSEPK;  Q9UY24, IPYR_PYRAB;  
Q8U438, IPYR_PYRFU;  O59570, IPYR_PYRHO;  Q8XWX1, IPYR_RALSO;  
Q98ER2, IPYR_RHILO;  Q92LH1, IPYR_RHIME;  Q9RGQ1, IPYR_RHORT;  
Q1RIN6, IPYR_RICBR;  Q92H74, IPYR_RICCN;  Q4UKW0, IPYR_RICFE;  
Q9ZCW5, IPYR_RICPR;  Q68WE9, IPYR_RICTY;  P65749, IPYR_SALTI;  
P65748, IPYR_SALTY;  P19117, IPYR_SCHPO;  Q43187, IPYR_SOLTU;  
Q9X8I9, IPYR_STRCO;  P50308, IPYR_SULAC;  Q97W51, IPYR_SULSO;  
Q974Y8, IPYR_SULTO;  P80507, IPYR_SYNY3;  P37981, IPYR_THEAC;  
Q8DHR2, IPYR_THEEB;  Q5JIY3, IPYR_THEKO;  P77992, IPYR_THELN;  
P38576, IPYR_THET8;  Q979E6, IPYR_THEVO;  Q9PQH6, IPYR_UREPA;  
Q9KP34, IPYR_VIBCH;  Q87SW1, IPYR_VIBPA;  Q8DE89, IPYR_VIBVU;  
Q7MPD2, IPYR_VIBVY;  Q8D274, IPYR_WIGBR;  Q8PH18, IPYR_XANAC;  
Q8P5M4, IPYR_XANCP;  P65750, IPYR_XYLFA;  P65751, IPYR_XYLFT;  
Q6C1T4, IPYR_YARLI;  P00817, IPYR_YEAST;  Q8ZB98, IPYR_YERPE;  
Q9C0T9, IPYR_ZYGBA;  Q0VD18, LHPP_BOVIN;  A5PLK2, LHPP_DANRE;  
Q9H008, LHPP_HUMAN;  Q9D7I5, LHPP_MOUSE;  Q5I0D5, LHPP_RAT;  
Q3B8E3, LHPP_XENLA;  Q9X015, MAZG_THEMA;  O29502, PPAC_ARCFU;  
C3PD52, PPAC_BACAA;  C3LG25, PPAC_BACAC;  Q81PH9, PPAC_BACAN;  
B7JRU3, PPAC_BACC0;  Q736P6, PPAC_BACC1;  B7IJP9, PPAC_BACC2;  
C1EXV7, PPAC_BACC3;  B7HA46, PPAC_BACC4;  B7HUD5, PPAC_BACC7;  
A7GQ01, PPAC_BACCN;  B9J353, PPAC_BACCQ;  Q81CE5, PPAC_BACCR;  
Q63AC7, PPAC_BACCZ;  Q6HHR6, PPAC_BACHK;  Q65E18, PPAC_BACLD;  
P56948, PPAC_BACME;  A8FJD5, PPAC_BACP2;  Q5WDX3, PPAC_BACSK;  
P37487, PPAC_BACSU;  A7ZAR2, PPAC_BACVZ;  A9VIG8, PPAC_BACWK;  
C0ZGL2, PPAC_BREBN;  Q97H75, PPAC_CLOAB;  Q9RRB7, PPAC_DEIRA;  
Q834N3, PPAC_ENTFA;  B1YLU2, PPAC_EXIS2;  C4L0S9, PPAC_EXISA;  
Q5FK05, PPAC_LACAC;  Q1GAB5, PPAC_LACDA;  Q04AP3, PPAC_LACDB;  
Q043J4, PPAC_LACGA;  A8YVH1, PPAC_LACH4;  Q74JD5, PPAC_LACJO;  
Q9CEM5, PPAC_LACLA;  Q88W32, PPAC_LACPL;  Q92BR1, PPAC_LISIN;  
C1KV95, PPAC_LISMC;  Q71ZM2, PPAC_LISMF;  B8DE62, PPAC_LISMH;  
Q8Y757, PPAC_LISMO;  A0AIQ0, PPAC_LISW6;  Q58025, PPAC_METJA;  
A0B5R0, PPAC_METTP;  Q8CUT9, PPAC_OCEIH;  A7X451, PPAC_STAA1;  
A6U325, PPAC_STAA2;  Q2FFH6, PPAC_STAA3;  Q2FWY1, PPAC_STAA8;  
A5IU87, PPAC_STAA9;  Q2YU53, PPAC_STAAB;  Q5HEK1, PPAC_STAAC;  
P65752, PPAC_STAAM;  P65753, PPAC_STAAN;  Q6GFD7, PPAC_STAAR;  
Q6G813, PPAC_STAAS;  A8Z2T4, PPAC_STAAT;  P65754, PPAC_STAAW;  
B9DMR8, PPAC_STACT;  Q5HN17, PPAC_STAEQ;  Q8CNN7, PPAC_STAES;  
Q4L7N2, PPAC_STAHJ;  Q49YW3, PPAC_STAS1;  Q3K0B5, PPAC_STRA1;  
Q8E4D4, PPAC_STRA3;  Q8DYS6, PPAC_STRA5;  C0M7N7, PPAC_STRE4;  
B4U4N8, PPAC_STREM;  P95765, PPAC_STRGC;  O68579, PPAC_STRMU;  
P65757, PPAC_STRP1;  Q04JL5, PPAC_STRP2;  P0DD14, PPAC_STRP3;  
B5E699, PPAC_STRP4;  Q5XDN3, PPAC_STRP6;  C1C8C3, PPAC_STRP7;  
P65759, PPAC_STRP8;  A2RG81, PPAC_STRPG;  B1ICV4, PPAC_STRPI;  
B8ZLD4, PPAC_STRPJ;  P65755, PPAC_STRPN;  P0DD15, PPAC_STRPQ;  
B2IR53, PPAC_STRPS;  B5XJY9, PPAC_STRPZ;  P65756, PPAC_STRR6;  
A4W395, PPAC_STRS2;  C0MGI9, PPAC_STRS7;  A3CPM5, PPAC_STRSV;  
A4VWZ2, PPAC_STRSY;  Q5M194, PPAC_STRT1;  Q5M5T1, PPAC_STRT2;  
Q03M65, PPAC_STRTD;  B9DTT7, PPAC_STRU0;  C1CFB5, PPAC_STRZJ;  
C1CLN3, PPAC_STRZP;  C1CSF2, PPAC_STRZT;  Q9WZ56, PPAC_THEMA;  
B7GL49, PPAX_ANOFW;  C3P0C8, PPAX_BACAA;  C3LED0, PPAX_BACAC;  
A0RKU8, PPAX_BACAH;  Q6HQY9, PPAX_BACAN;  B7JFI8, PPAX_BACC0;  
Q72XV8, PPAX_BACC1;  B7IPS5, PPAX_BACC2;  C1EZE2, PPAX_BACC3;  
B7HEG2, PPAX_BACC4;  B7HWY7, PPAX_BACC7;  B9J4R5, PPAX_BACCQ;  
Q815I8, PPAX_BACCR;  Q631J2, PPAX_BACCZ;  Q9K6Y7, PPAX_BACHD;  
Q6HBC8, PPAX_BACHK;  A8FHS1, PPAX_BACP2;  Q9JMQ2, PPAX_BACSU;  
A7Z971, PPAX_BACVZ;  A9VQ75, PPAX_BACWK;  Q8R821, PPAX_CALS4;  
Q8XIY6, PPAX_CLOPE;  Q928B2, PPAX_LISIN;  C1KYP8, PPAX_LISMC;  
Q71WU6, PPAX_LISMF;  B8DBN0, PPAX_LISMH;  Q8Y4G3, PPAX_LISMO;  
A0ALG5, PPAX_LISW6;  Q8ENK3, PPAX_OCEIH;  Q67YC0, PPSP1_ARATH;  
Q9FZ62, PPSP2_ARATH;  Q9SU92, PPSP3_ARATH;  Q5E9Y6, PRUNE_BOVIN;  
Q86TP1, PRUNE_HUMAN;  Q8BIW1, PRUNE_MOUSE;  Q6AYG3, PRUNE_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
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