ENZYME entry: EC 4.1.1.1

Accepted Name
Pyruvate decarboxylase.
Alternative Name(s)
2-oxo-acid carboxy-lyase.
Alpha-carboxylase.
Alpha-ketoacid carboxylase.
Pyruvic decarboxylase.
Reaction catalysed
A 2-oxo acid <=> an aldehyde + CO(2)
Cofactor(s)
Thiamine diphosphate.
Comment(s)
Also catalyzes acyloin formation.
Cross-references
PROSITEPDOC00166
BRENDA4.1.1.1
EC2PDB4.1.1.1
ExplorEnz4.1.1.1
PRIAM enzyme-specific profiles4.1.1.1
KEGG Ligand Database for Enzyme Nomenclature4.1.1.1
IUBMB Enzyme Nomenclature4.1.1.1
IntEnz4.1.1.1
MEDLINEFind literature relating to 4.1.1.1
MetaCyc4.1.1.1
UniProtKB/Swiss-Prot
O82647, PDC1_ARATH;  P83779, PDC1_CANAL;  Q6FJA3, PDC1_CANGA;  
Q12629, PDC1_KLULA;  P33149, PDC1_KLUMA;  P28516, PDC1_MAIZE;  
A2Y5L9, PDC1_ORYSI;  Q0DHF6, PDC1_ORYSJ;  P51850, PDC1_PEA;  
Q09737, PDC1_SCHPO;  P51845, PDC1_TOBAC;  P06169, PDC1_YEAST;  
Q9FFT4, PDC2_ARATH;  Q05326, PDC2_MAIZE;  A2XFI3, PDC2_ORYSI;  
Q10MW3, PDC2_ORYSJ;  P51851, PDC2_PEA;  Q92345, PDC2_SCHPO;  
P51846, PDC2_TOBAC;  Q9M039, PDC3_ARATH;  Q05327, PDC3_MAIZE;  
A2YQ76, PDC3_ORYSI;  Q0D3D2, PDC3_ORYSJ;  Q9P7P6, PDC3_SCHPO;  
Q9M040, PDC4_ARATH;  O42873, PDC4_SCHPO;  P16467, PDC5_YEAST;  
P26263, PDC6_YEAST;  Q4WXX9, PDC_ASPFU;  Q2UKV4, PDC_ASPOR;  
P51844, PDC_ASPPA;  Q0CNV1, PDC_ASPTN;  P87208, PDC_EMENI;  
P34734, PDC_HANUV;  P33287, PDC_NEUCR;  P06672, PDC_ZYMMO;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
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