ENZYME class: 4.1

Release of 11-May-16


Lyases
Carbon-carbon lyases

All UniProtKB/Swiss-Prot entries corresponding to class 4.1.-.-.

The following ENZYME entries belong to class 4.1.-.-:

4.1.1.1      Pyruvate decarboxylase
4.1.1.2      Oxalate decarboxylase
4.1.1.3      Oxaloacetate decarboxylase
4.1.1.4      Acetoacetate decarboxylase
4.1.1.5      Acetolactate decarboxylase
4.1.1.6      Aconitate decarboxylase
4.1.1.7      Benzoylformate decarboxylase
4.1.1.8      Oxalyl-CoA decarboxylase
4.1.1.9      Malonyl-CoA decarboxylase
4.1.1.10     Transferred entry: 4.1.1.12
4.1.1.11     Aspartate 1-decarboxylase
4.1.1.12     Aspartate 4-decarboxylase
4.1.1.13     Deleted entry
4.1.1.14     Valine decarboxylase
4.1.1.15     Glutamate decarboxylase
4.1.1.16     Hydroxyglutamate decarboxylase
4.1.1.17     Ornithine decarboxylase
4.1.1.18     Lysine decarboxylase
4.1.1.19     Arginine decarboxylase
4.1.1.20     Diaminopimelate decarboxylase
4.1.1.21     Phosphoribosylaminoimidazole carboxylase
4.1.1.22     Histidine decarboxylase
4.1.1.23     Orotidine-5'-phosphate decarboxylase
4.1.1.24     Aminobenzoate decarboxylase
4.1.1.25     Tyrosine decarboxylase
4.1.1.26     Transferred entry: 4.1.1.28
4.1.1.27     Transferred entry: 4.1.1.28
4.1.1.28     Aromatic-L-amino-acid decarboxylase
4.1.1.29     Sulfinoalanine decarboxylase
4.1.1.30     Pantothenoylcysteine decarboxylase
4.1.1.31     Phosphoenolpyruvate carboxylase
4.1.1.32     Phosphoenolpyruvate carboxykinase (GTP)
4.1.1.33     Diphosphomevalonate decarboxylase
4.1.1.34     Dehydro-L-gulonate decarboxylase
4.1.1.35     UDP-glucuronate decarboxylase
4.1.1.36     Phosphopantothenoylcysteine decarboxylase
4.1.1.37     Uroporphyrinogen decarboxylase
4.1.1.38     Phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.39     Ribulose-bisphosphate carboxylase
4.1.1.40     Hydroxypyruvate decarboxylase
4.1.1.41     Methylmalonyl-CoA decarboxylase
4.1.1.42     Carnitine decarboxylase
4.1.1.43     Phenylpyruvate decarboxylase
4.1.1.44     4-carboxymuconolactone decarboxylase
4.1.1.45     Aminocarboxymuconate-semialdehyde decarboxylase
4.1.1.46     o-pyrocatechuate decarboxylase
4.1.1.47     Tartronate-semialdehyde synthase
4.1.1.48     Indole-3-glycerol-phosphate synthase
4.1.1.49     Phosphoenolpyruvate carboxykinase (ATP)
4.1.1.50     Adenosylmethionine decarboxylase
4.1.1.51     3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
4.1.1.52     6-methylsalicylate decarboxylase
4.1.1.53     Phenylalanine decarboxylase
4.1.1.54     Dihydroxyfumarate decarboxylase
4.1.1.55     4,5-dihydroxyphthalate decarboxylase
4.1.1.56     3-oxolaurate decarboxylase
4.1.1.57     Methionine decarboxylase
4.1.1.58     Orsellinate decarboxylase
4.1.1.59     Gallate decarboxylase
4.1.1.60     Stipitatonate decarboxylase
4.1.1.61     4-hydroxybenzoate decarboxylase
4.1.1.62     Gentisate decarboxylase
4.1.1.63     Protocatechuate decarboxylase
4.1.1.64     2,2-dialkylglycine decarboxylase (pyruvate)
4.1.1.65     Phosphatidylserine decarboxylase
4.1.1.66     Uracil-5-carboxylate decarboxylase
4.1.1.67     UDP-galacturonate decarboxylase
4.1.1.68     5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
4.1.1.69     3,4-dihydroxyphthalate decarboxylase
4.1.1.70     Glutaconyl-CoA decarboxylase
4.1.1.71     2-oxoglutarate decarboxylase
4.1.1.72     Branched-chain-2-oxoacid decarboxylase
4.1.1.73     Tartrate decarboxylase
4.1.1.74     Indolepyruvate decarboxylase
4.1.1.75     5-guanidino-2-oxopentanoate decarboxylase
4.1.1.76     Arylmalonate decarboxylase
4.1.1.77     2-oxo-3-hexenedioate decarboxylase
4.1.1.78     Acetylenedicarboxylate decarboxylase
4.1.1.79     Sulfopyruvate decarboxylase
4.1.1.80     4-hydroxyphenylpyruvate decarboxylase
4.1.1.81     Threonine-phosphate decarboxylase
4.1.1.82     Phosphonopyruvate decarboxylase
4.1.1.83     4-hydroxyphenylacetate decarboxylase
4.1.1.84     D-dopachrome decarboxylase
4.1.1.85     3-dehydro-L-gulonate-6-phosphate decarboxylase
4.1.1.86     Diaminobutyrate decarboxylase
4.1.1.87     Malonyl-S-ACP decarboxylase
4.1.1.88     Biotin-independent malonate decarboxylase
4.1.1.89     Biotin-dependent malonate decarboxylase
4.1.1.90     Peptidyl-glutamate 4-carboxylase
4.1.1.91     Salicylate decarboxylase
4.1.1.92     Indole-3-carboxylate decarboxylase
4.1.1.93     Pyrrole-2-carboxylate decarboxylase
4.1.1.94     Ethylmalonyl-CoA decarboxylase
4.1.1.95     L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
4.1.1.96     Carboxynorspermidine decarboxylase
4.1.1.97     2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
4.1.1.98     4-hydroxy-3-polyprenylbenzoate decarboxylase
4.1.1.99     Phosphomevalonate decarboxylase
4.1.1.100    Prephenate decarboxylase
4.1.1.101    Malolactic enzyme
4.1.1.102    Phenacrylate decarboxylase
4.1.1.n1     Transferred entry: 4.1.1.97
4.1.1.n2     Transferred entry: 4.1.1.94
4.1.2.1      Transferred entry: 4.1.3.16
4.1.2.2      Ketotetrose-phosphate aldolase
4.1.2.3      Deleted entry
4.1.2.4      Deoxyribose-phosphate aldolase
4.1.2.5      L-threonine aldolase
4.1.2.6      Deleted entry
4.1.2.7      Transferred entry: 4.1.2.13
4.1.2.8      Indole-3-glycerol-phosphate lyase
4.1.2.9      Phosphoketolase
4.1.2.10     (R)-mandelonitrile lyase
4.1.2.11     Hydroxymandelonitrile lyase
4.1.2.12     2-dehydropantoate aldolase
4.1.2.13     Fructose-bisphosphate aldolase
4.1.2.14     2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.15     Transferred entry: 2.5.1.54
4.1.2.16     Transferred entry: 2.5.1.55
4.1.2.17     L-fuculose-phosphate aldolase
4.1.2.18     2-dehydro-3-deoxy-L-pentonate aldolase
4.1.2.19     Rhamnulose-1-phosphate aldolase
4.1.2.20     2-dehydro-3-deoxyglucarate aldolase
4.1.2.21     2-dehydro-3-deoxy-6-phosphogalactonate aldolase
4.1.2.22     Fructose-6-phosphate phosphoketolase
4.1.2.23     3-deoxy-D-manno-octulosonate aldolase
4.1.2.24     Dimethylaniline-N-oxide aldolase
4.1.2.25     Dihydroneopterin aldolase
4.1.2.26     Phenylserine aldolase
4.1.2.27     Sphinganine-1-phosphate aldolase
4.1.2.28     2-dehydro-3-deoxy-D-pentonate aldolase
4.1.2.29     5-dehydro-2-deoxyphosphogluconate aldolase
4.1.2.30     17-alpha-hydroxyprogesterone aldolase
4.1.2.31     Transferred entry: 4.1.3.16
4.1.2.32     Trimethylamine-oxide aldolase
4.1.2.33     Fucosterol-epoxide lyase
4.1.2.34     4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
4.1.2.35     Propioin synthase
4.1.2.36     Lactate aldolase
4.1.2.37     Transferred entry: 4.1.2.46 and 4.1.2.47
4.1.2.38     Benzoin aldolase
4.1.2.39     Transferred entry: 4.1.2.46 and 4.1.2.47
4.1.2.40     Tagatose-bisphosphate aldolase
4.1.2.41     Vanillin synthase
4.1.2.42     D-threonine aldolase
4.1.2.43     3-hexulose-6-phosphate synthase
4.1.2.44     2,3-epoxybenzoyl-CoA dihydrolase
4.1.2.45     Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
4.1.2.46     Aliphatic (R)-hydroxynitrile lyase
4.1.2.47     (S)-hydroxynitrile lyase
4.1.2.48     Low-specificity L-threonine aldolase
4.1.2.49     L-allo-threonine aldolase
4.1.2.50     6-carboxytetrahydropterin synthase
4.1.2.51     2-dehydro-3-deoxy-D-gluconate aldolase
4.1.2.52     4-hydroxy-2-oxoheptanedioate aldolase
4.1.2.53     2-keto-3-deoxy-L-rhamnonate aldolase
4.1.2.54     L-threo-3-deoxy-hexylosonate aldolase
4.1.2.55     2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate
             aldolase
4.1.2.56     2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate synthase
4.1.2.57     Sulfofructosephosphate aldolase
4.1.2.n1     Transferred entry: 4.1.2.44
4.1.2.n2     2-hydroxyphytanoyl-CoA lyase
4.1.2.n3     Transferred entry: 4.1.2.53
4.1.2.n4     Transferred entry: 4.1.2.52
4.1.2.n5     Transferred entry: 2.2.1.10
4.1.2.n6     Transferred entry: 4.1.2.56
4.1.3.1      Isocitrate lyase
4.1.3.2      Transferred entry: 2.3.3.9
4.1.3.3      N-acetylneuraminate lyase
4.1.3.4      Hydroxymethylglutaryl-CoA lyase
4.1.3.5      Transferred entry: 2.3.3.10
4.1.3.6      Citrate (pro-3S)-lyase
4.1.3.7      Transferred entry: 2.3.3.1
4.1.3.8      Transferred entry: 2.3.3.8
4.1.3.9      Transferred entry: 2.3.3.11
4.1.3.10     Transferred entry: 2.3.3.7
4.1.3.11     Transferred entry: 2.3.3.12
4.1.3.12     Transferred entry: 2.3.3.13
4.1.3.13     Oxalomalate lyase
4.1.3.14     L-erythro-3-hydroxyaspartate aldolase
4.1.3.15     Transferred entry: 2.2.1.5
4.1.3.16     4-hydroxy-2-oxoglutarate aldolase
4.1.3.17     4-hydroxy-4-methyl-2-oxoglutarate aldolase
4.1.3.18     Transferred entry: 2.2.1.6
4.1.3.19     Transferred entry: 2.5.1.56
4.1.3.20     Transferred entry: 2.5.1.57
4.1.3.21     Transferred entry: 2.3.3.14
4.1.3.22     Citramalate lyase
4.1.3.23     Transferred entry: 2.3.3.2
4.1.3.24     Malyl-CoA lyase
4.1.3.25     (S)-citramalyl-CoA lyase
4.1.3.26     3-hydroxy-3-isohexenylglutaryl-CoA lyase
4.1.3.27     Anthranilate synthase
4.1.3.28     Transferred entry: 2.3.3.3
4.1.3.29     Transferred entry: 2.3.3.4
4.1.3.30     Methylisocitrate lyase
4.1.3.31     Transferred entry: 2.3.3.5
4.1.3.32     2,3-dimethylmalate lyase
4.1.3.33     Transferred entry: 2.3.3.6
4.1.3.34     Citryl-CoA lyase
4.1.3.35     (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
4.1.3.36     1,4-dihydroxy-2-naphthoyl-CoA synthase
4.1.3.37     Transferred entry: 2.2.1.7
4.1.3.38     Aminodeoxychorismate lyase
4.1.3.39     4-hydroxy-2-oxovalerate aldolase
4.1.3.40     Chorismate lyase
4.1.3.41     3-hydroxy-D-aspartate aldolase
4.1.3.42     (4S)-4-hydroxy-2-oxoglutarate aldolase
4.1.3.43     4-hydroxy-2-oxohexanoate aldolase
4.1.3.44     tRNA 4-demethylwyosine synthase (AdoMet-dependent)
4.1.3.45     3-hydroxybenzoate synthase
4.1.3.46     (R)-citramalyl-CoA lyase
4.1.3.n1     Transferred entry: 4.1.3.43
4.1.99.1     Tryptophanase
4.1.99.2     Tyrosine phenol-lyase
4.1.99.3     Deoxyribodipyrimidine photo-lyase
4.1.99.4     Transferred entry: 3.5.99.7
4.1.99.5     Aldehyde oxygenase (deformylating)
4.1.99.6     Transferred entry: 4.2.3.6
4.1.99.7     Transferred entry: 4.2.3.9
4.1.99.8     Transferred entry: 4.2.3.119 and 4.2.3.120
4.1.99.9     Transferred entry: 4.2.3.15
4.1.99.10    Transferred entry: 4.2.3.16
4.1.99.11    Benzylsuccinate synthase
4.1.99.12    3,4-dihydroxy-2-butanone-4-phosphate synthase
4.1.99.13    (6-4)DNA photolyase
4.1.99.14    Spore photoproduct lyase
4.1.99.15    Deleted entry
4.1.99.16    Geosmin synthase
4.1.99.17    Phosphomethylpyrimidine synthase
4.1.99.18    Cyclic pyranopterin phosphate synthase
4.1.99.19    2-iminoacetate synthase
4.1.99.20    3-amino-4-hydroxybenzoate synthase
4.1.99.21    Transferred entry: 4.2.3.153